Quantifying the effects of cultivation mode and sprouting stage on tea bud morphology and chemical quality. [PDF]
Zhu W +7 more
europepmc +1 more source
A large‐scale, high‐resolution antimicrobial resistance (AMR) surveillance in Hong Kong community sewage combining short‐ and long‐read sequencing. The resistome profile is comprehensively characterized, and this upstream sampling strategy demonstrated superiority in reflecting the human gut resistome.
Jiahui Ding +11 more
wiley +1 more source
Retrospective chart review and clinical experience of using fully ablative carbon dioxide laser assisted photodynamic therapy to treat basal cell carcinoma with 2 year outcomes. [PDF]
Godinho Ramos S +6 more
europepmc +1 more source
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
Indigenous fungi inoculation drives organic carbon accumulation and phosphorus transformation in coal gangue-based artificial soil: role of mineral-bioactivation. [PDF]
Zhang H +11 more
europepmc +1 more source
PORTABLE CONCRETE MIX DESIGN CHART FOR CONCRETE PRODUCTION
openaire +1 more source
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel +19 more
wiley +1 more source
Mixed nitrogen forms enhance growth and photosynthetic nitrogen use efficiency by optimizing nitrogen metabolism and leaf N allocation in Gisela 6 cherry rootstock. [PDF]
Xu X +11 more
europepmc +1 more source
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source

