Results 11 to 20 of about 725,473 (251)

Circadian patterns in postvoid residual and voided percentage among older women with urinary incontinence [PDF]

open access: yes, 2020
Background: Women with urinary incontinence incur an increased risk of elevated postvoid residual (PVR) volume and impaired voiding efficiency (i.e., voided percentage (Void%)), but the clinical significance of these parameters remains poorly described ...
Decalf, Veerle   +6 more
core   +2 more sources

Analog-digital codesign using coarse quantization [PDF]

open access: yes, 2005
This thesis shows that coarse quantization can lead to mixed-signal systems with lower costs but system parameters will change. The explicit reconsideration of functional specifications, facilitated by the Y-chart approach, is therefore essential for the
Kokkeler, André Bernardus Joseph
core   +3 more sources

Redesigning the 'choice architecture' of hospital prescription charts: a mixed methods study incorporating in situ simulation testing. [PDF]

open access: yes, 2014
Objectives: To incorporate behavioural insights into the user-centred design of an inpatient prescription chart (Imperial Drug Chart Evaluation and Adoption Study, IDEAS chart) and to determine whether changes in the content and design of prescription ...
Bicknell, C   +9 more
core   +1 more source

Space Weather Action Center [PDF]

open access: yes, 2009
This is a revised "Tracking a Solar Storm-Student Observation Network" with a new format and Web site. The Space Weather Action Center (SWAC) allows students to use near real time data and track a solar storm.

core   +2 more sources

Density dependence of the pairing interaction and pairing correlation in unstable nuclei

open access: yes, 2015
This work aims at a global assessment of the effect of the density dependence of the zero-range pairing interaction. Systematic Skyrme-Hartree-Fock-Bogoliubov calculations with the volume, surface and mixed pairing forces are carried out to study the ...
Changizi, S. A., Qi, Chong
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

UHE nuclei propagation and the interpretation of the ankle in the cosmic-ray spectrum

open access: yes, 2005
We consider the stochastic propagation of high-energy protons and nuclei in the cosmological microwave and infrared backgrounds, using revised photonuclear cross-sections and following primary and secondary nuclei in the full 2D nuclear chart. We confirm
A. V. Olinto   +19 more
core   +3 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

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