Results 151 to 160 of about 443,069 (407)

A Rare Case of Mixed Connective Tissue Disease (MCTD) with Intricate Features of Lupus, Polymyositis and Rheumatoid Arthritis Presenting with Severe Myositis.

Journal of clinical and diagnostic research : JCDR, 2015
Mixed connective tissue disease (MCTD) includes clinical and laboratorial manifestations of systemic lupus erythematosus, scleroderma and polymyositis along with high titres of anti-U1RNP antibodies.
L. S., Kadavanu Tony, Raghupathy, S. V., Balakrishna Malepati   +4 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Morbidity Pattern Among Out-Patients Attending Urban Health Training Centre in Srinagar [PDF]

, 2018
The current study was designed to identify the morbidity pattern of out-patients attending Urban Health Training Centre in an urban area of a medical college in Srinagar, Pauri Garhwal district, Uttarakhand, North India.
Ali, H. (Haroon), Kumar, S. (Santosh), Raj, A. (Abhishek), Singh, A. K. (Amit)   +3 more
core   +2 more sources

Pulmonary hypertension associated with connective tissue disease

Indian Journal of Rheumatology, 2017
Pulmonary hypertension (PH) is an important cause of morbidity and mortality in connective tissue diseases (CTDs). CTDs may cause PH due to several mechanisms; pulmonary arterial hypertension, associated interstitial lung disease, neuromuscular disease ...
Srinivas Rajagopala, Molly Mary Thabah
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Tenomodulin expression in the periodontal ligament enhances cellular adhesion. [PDF]

, 2013
Tenomodulin (Tnmd) is a type II transmembrane protein characteristically expressed in dense connective tissues such as tendons and ligaments. Its expression in the periodontal ligament (PDL) has also been demonstrated, though the timing and function ...
Chung, Ung-Il, Docheva, Denitsa, Hiraki, Yuji, Hojo, Hironori, Komiyama, Yuske, Nakajima, Keiji, Ohba, Shinsuke, Shimohata, Nobuyuki, Shukunami, Chisa, Takato, Tsuyoshi, Yano, Fumiko   +10 more
core   +3 more sources

To sleep perchance to dream unusual bradyarrhythmia in an adolescent

IHJ Cardiovascular Case Reports, 2018
Connective tissue disorders may involve the conduction system. A 16-year-old patient with known mixed connective tissue disorder (MTCD) presented with bradyarrhythmia.
Nandini Madan, Parijia Sharedall
doaj  

TopSpace: spatial topic modeling for unsupervised discovery of multicellular spatial tissue structures in multiplex imaging [PDF]

arXiv
Motivation: Understanding the spatial architecture of tissues is essential for decoding the complex interactions within cellular ecosystems and their implications for disease pathology and clinical outcomes. Recent advances in multiplex imaging technologies have enabled high-resolution profiling of cellular phenotypes and their spatial distributions ...
arxiv  

Fluctuations in anti-nRNP levels in patients with mixed connective tissue disease are related to disease activity as part of a polyclonal B cell response. [PDF]

, 1986
P. M. Houtman, C. G. M. Kallenberg, P. C. Limburg, M. A. van Leeuwen, M. H. van Rijswijk, T. H. The   +5 more
openalex   +1 more source

Mixed Connective Tissue Disease [PDF]

Proceedings of the Royal Society of Medicine, 1974
D M Thompson, C M Ridley, R A L Sutton
openaire   +3 more sources