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Mixed Connective Tissue Disease
Current Opinion in Rheumatology, 2000A defining feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribonucleoprotein (RNP) complex, but other autoantibodies in MCTD have recently been described. Research has also further elucidated the immune responses directed against U1-RNP in humans and in murine models of disease.
R W, Hoffman, E L, Greidinger
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Mixed Connective Tissue Disease
2008Mixed connective tissue disease (MCTD) is a condition characterized by the overlap of features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and polydermatomyositis (PM/DM) in association with high titers of antibodies against a ribonuclear protein (RNP).
MOSCA, MARTA +2 more
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The Pediatric clinics of North America, 2018
Juvenile systemic lupus erythematosus (jSLE), mixed connective tissue disease (jMCTD), and Sjögren syndrome (jSS) are systemic autoimmune and inflammatory disorders with distinct patterns of organ involvement.
Stacey E Tarvin, K. O’neil
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Juvenile systemic lupus erythematosus (jSLE), mixed connective tissue disease (jMCTD), and Sjögren syndrome (jSS) are systemic autoimmune and inflammatory disorders with distinct patterns of organ involvement.
Stacey E Tarvin, K. O’neil
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Pulmonary Manifestations of Systemic Sclerosis and Mixed Connective Tissue Disease.
Clinics in Chest Medicine, 2019Systemic sclerosis (SSc) is a rare disease characterized by widespread collagen deposition resulting in fibrosis. Although skin involvement is the most common manifestation and also the one that determines the classification of disease, mortality in SSc ...
A. Perelas, A. Arrossi, K. Highland
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Mixed Connective Tissue Disease
Radiologic Clinics of North America, 1988MCTD is characterized by clinical features that overlap those of several of the classic rheumatic and connective tissue disorders. Although MCTD has been distinguished from them by the presence of antibodies to an RNP and by specific immunoregulatory T cell circuit abnormalities, its definitive placement among the classic disorders remains ...
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Mixed connective tissue disease revisited
Clinical Rheumatology, 1982SCOPUS: ar.j ; info:eu-repo/semantics ...
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Mixed Connective Tissue Disease
Archives of Internal Medicine, 1976• Three patients with mixed connective tissue disease (MCTD) had clinical features that included a high incidence of Raynaud phenomenon, arthritis, myositis, and swollen hands. The diagnostic laboratory test result was the presence of high titers of antibody to extractable nuclear antigen.
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Mixed connective tissue disease in childhood
Pediatrics International, 1993AbstractSince 1981, 21 children diagnosed with mixed connective tissue disease (MCTD) have been reported in detail in the literature in Japan. Overlapping clinical features and laboratory findings of these children were analyzed according to the established criteria of the Ministry of Health and Welfare, Japan.
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