Results 341 to 350 of about 443,069 (407)

Pediatric Mixed Connective Tissue Disease

Current Rheumatology Reports, 2016
Pediatric-onset mixed connective tissue disease is among the rare disease entities in pediatric rheumatology and includes features of arthritis, polymyositis/dermatomyositis, systemic lupus erythematosus, and systemic sclerosis. Accurate recognition and diagnosis of the disease is paramount to prevent long-term morbidity.
Roberta A. Berard, Roberta A. Berard, Ronald M. Laxer   +2 more
openaire   +4 more sources

Clinical presentation, course, and prognosis of patients with mixed connective tissue disease: A multicenter retrospective cohort

Journal of Internal Medicine, 2023
The objective of this study is to better characterize the features and outcomes of a large population of patients with mixed connective tissue disease (MCTD).
K. Chevalier, B. Thoreau, Marc Michel, Bertrand Godeau, C. Agard, T. Papo, K. Sacré, R. Seror, Xavier Mariette, Patrice Cacoub, Y. Benhamou, Hervé Lévesque, Cécile Goujard, Olivier Lambotte, B. Bonnotte, Maxime Samson, F. Ackermann, Jean Schmidt, Pierre Duhaut, Jean-Emmanuel Kahn, Thomas Hanslik, N. Costedoat-Chalumeau, Benjamin Terrier, A. Régent, B. Dunogué, Pascal Cohen, V. Guern, Eric Hachulla, B. Chaigne, L. Mouthon   +29 more
semanticscholar   +1 more source

Mixed connective tissue disease

Clinics in Dermatology, 1985
Abstract Mixed connective tissue disease (MCTD) was first described by Gordon Sharp, 1 in 1972, as a distinct connective tissue disorder characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS), and dermato/polymyositis (DP/PM).
David T. Schreiner, Joseph L. Jorizzo
  +9 more sources

Mixed Connective Tissue Disease

Archives of Internal Medicine, 1976
Three patients with mixed connective tissue disease (MCTD) had clinical features that included a high incidence of Raynaud phenomenon, arthritis, myositis, and swollen hands. The diagnostic laboratory test result was the presence of high titers of antibody to extractable nuclear antigen.
Wilfred Minkin, Nathan B. Rabhan
openaire   +5 more sources

Mixed Connective Tissue Disease

Current Opinion in Rheumatology, 2000
A defining feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribonucleoprotein (RNP) complex, but other autoantibodies in MCTD have recently been described. Research has also further elucidated the immune responses directed against U1-RNP in humans and in murine models of disease.
Eric L. Greidinger, Robert W. Hoffman
openaire   +3 more sources

Mixed Connective Tissue Disease

AJN, American Journal of Nursing, 1977
Coping with chronic illness has become a personal experience for me. For the past 13 years, I have gone through various stages of coping with mixed connective tissue disease (MCTD), a rare collagen-vascular disease of unknown origin that resembles scleroderma, lupus erythematosus, and polymyositis.
openaire   +6 more sources

Osteoporosis in mixed connective tissue disease

Clinical Rheumatology, 2003
The existence of osteoporosis in 58 postmenopausal women with mixed connective tissue disease (MCTD) was investigated. The mean bone mineral density assessed by dual energy X-ray absorptiometry in the lumbar spine was decreased in 25.8% of the patients, reflecting osteoporosis (T score < -2.5).
Bodolay, Edit, Bettembuk, Péter, Balogh, Á., Szekanecz, Zoltán   +3 more
openaire   +3 more sources

Mixed Connective Tissue Disease

2008
Mixed connective tissue disease (MCTD) is a condition characterized by the overlap of features of systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and polydermatomyositis (PM/DM) in association with high titers of antibodies against a ribonuclear protein (RNP).
MOSCA, MARTA, R. Talarico, S. Bombardieri   +2 more
openaire   +4 more sources

Mixed connective tissue disease

Lupus, 2006
Mixed connective tissue disease (MCTD) was first described in 1972 as a disease syndrome with overlapping features of systemic sclerosis, systemic lupus erythematosus (SLE) and polymyositis associated with antibodies to RNAse sensitive extractable nuclear antigen.
openaire   +3 more sources