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Tissue Antigens, 2016
Mixed connective tissue disease (MCTD) is a systemic autoimmune disease, originally defined as a connective tissue inflammatory syndrome with overlapping features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), polymyositis ...
A. Paradowska-Gorycka +8 more
semanticscholar +2 more sources
Mixed connective tissue disease (MCTD) is a systemic autoimmune disease, originally defined as a connective tissue inflammatory syndrome with overlapping features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), polymyositis ...
A. Paradowska-Gorycka +8 more
semanticscholar +2 more sources
Mixed Connective Tissue Disease
Radiologic Clinics of North America, 1988MCTD is characterized by clinical features that overlap those of several of the classic rheumatic and connective tissue disorders. Although MCTD has been distinguished from them by the presence of antibodies to an RNP and by specific immunoregulatory T cell circuit abnormalities, its definitive placement among the classic disorders remains ...
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Stroke and Mixed Connective Tissue Disease
Journal of Child Neurology, 1993We describe the clinical presentation and course of two girls with cerebrovascular disease and mixed connective tissue disease. One developed rapid onset hemiparesis and aphasia secondary to left internal carotid artery occlusion. She experienced a complete recovery after treatment with prednisone and cyclophosphamide.
David D. Sherry +2 more
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Mixed connective tissue disease in childhood
Pediatrics International, 1993AbstractSince 1981, 21 children diagnosed with mixed connective tissue disease (MCTD) have been reported in detail in the literature in Japan. Overlapping clinical features and laboratory findings of these children were analyzed according to the established criteria of the Ministry of Health and Welfare, Japan.
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MCTD – Mixed Connective Tissue Disease
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2005ZusammenfassungDie Mixed connective tissue disease (MCTD) zeichnet sich als eine Krankheitsentität mit Überlappungssymptomen des Lupus erythematodes (LE), der systemischen Sklerodermie (SSc), Dermatomyositis/Polymyositis (DM/PM) sowie der Rheumatoid‐Arthritis (RA) aus.
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Mixed Connective Tissue Disease
Southern Medical Journal, 1982Mixed connective tissue disease is characterized by overlapping features of classic connective tissue diseases and the presence of antibodies to ribonucleoprotein. Placement of this disorder among the classic disorders still remains controversial. The clinical features, prognosis, and therapeutic features of this syndrome are discussed in this report.
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Mixed connective tissue disease in siblings
Arthritis & Rheumatism, 1978AbstractMixed connective tissue disease (MCTD) was diagnosed in a brother and sister, and 18 additional family members spanning three generations were studied to detect evidence of autoimmune disease. Symptoms or signs of MCTD without complete expression of the disease were found in 8 relatives of the original cases. Antibodies to ribonucleoprotein and
Janet J. Kapur +3 more
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MIXED CONNECTIVE TISSUE DISEASE IN CHILDREN
Rheumatology, 1978A diagnosis of Mixed Connective Tissue Disease (MCTD) had been made in five juveniles in the past two years. All have antibodies to the ribonucleoprotein (RNP) component of extractable fluorescence pattern. No child has had life-threatening complications, though three have required steroids to control their symptoms.
A. Howard +3 more
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Treatment of Mixed Connective Tissue Disease
Rheumatic Disease Clinics of North America, 2005Mixed connective tissue disease (MCTD) is believed to be incurable and seems to have a variable prognosis. Some patients have a mild self-limited disease, whereas others develop major organ involvement that requires aggressive treatment. Because no controlled clinical trials have been performed to guide therapy in MCTD, treatment strategies must rely ...
Paul Kim, Jennifer M. Grossman
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Amyloidosis in Mixed Connective Tissue Disease
Scandinavian Journal of Rheumatology, 1989The syndrome mixed connective tissue disease (MCTD) has certain features in common with systemic lupus erythematosus (SLE), systemic sclerosis (SS), rheumatoid arthritis (RA) and polymyositis (PM) (1). The diagnosis of MCTD requires the presence of features of at least two systemic connective tissue diseases, high serum titres of antiribonucleoprotein ...
T. Törnroth +3 more
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