Alphonsine Imanishimwe,1,2 Celestin Banamwana,1 Georges Bucyibaruta,3,4 Christian Nsanzabaganwa,5 Faustin Ntirenganya,2,4 Erigene Rutayisire1 1School of Public Health, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda; 2Global
Imanishimwe A +5 more
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External immune sentinels in the seawater ecosystem: the specialization of bivalve hemocytes. [PDF]
Rey-Campos M +6 more
europepmc +1 more source
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
The effect of different surface treatment on shear bond strength of soft and hard liners to CAD-CAM and conventional denture base resins: <i>in vitro</i> comparative study. [PDF]
Albazroun Z +9 more
europepmc +1 more source
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih +12 more
wiley +1 more source
Assessment of three broadleaf weed species classification in rice field using UAV hyperspectral imaging and machine learning. [PDF]
Sulaiman N +5 more
europepmc +1 more source
Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel +19 more
wiley +1 more source
A highly specific fluorescent probe with facile pretreatment for rapid and accurate detection of sulfur dioxide residues in wolfberry (<i>Lycium barbarum L</i>.). [PDF]
Ge Y +12 more
europepmc +1 more source
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu +11 more
wiley +1 more source
Porcine salivary carbonic anhydrase VI is involved in the pathogenesis of disease. [PDF]
Matas-Quintanilla M +3 more
europepmc +1 more source

