Results 51 to 60 of about 2,457,267 (238)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
ON A PROBLEM FOR THE LOADED MIXED TYPE EQUATION WITH FRACTIONAL DERIVATIVE
Vestnik KRAUNC: Fiziko-Matematičeskie Nauki, 2016 An existence and an uniqueness of solution of local boundary value problem with discontinuous matching condition for the loaded parabolic-hyperbolic equation involving the Caputo fractional derivative and Riemann-Liouville integrals have been ...
Abdullaev, O.K.
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
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Bruno Pini Mathematical Analysis Seminar, 2018 In this seminar we illustrate some results of maximal regularity for the Cauchy-Dirichlet mixed problem, with a fractional time derivative of Caputo type in spaces of continuous and Hölder continuous functions.
Davide Guidetti
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Journal of Function Spaces, 2020 This paper considers nonlinear fractional mixed Volterra-Fredholm integro-differential equation with a nonlocal initial condition. We propose a fixed-point approach to investigate the existence, uniqueness, and Hyers-Ulam-Rassias stability of solutions ...
Somia Khaldi +2 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Journal of Function Spaces, 2022 In this work, an algorithm for finding numerical solutions of linear fractional delay-integro-differential equations (LFDIDEs) of variable-order (VO) is introduced.
Kamal R. Raslan +4 more
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FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source