Results 61 to 70 of about 34,540 (263)

Measuring quantum relative entropy with finite-size effect [PDF]

open access: yesQuantum
We study the estimation of relative entropy $D(\rho\|\sigma)$ when $\sigma$ is known. We show that the Cramér-Rao type bound equals the relative varentropy. Our estimator attains the Cramér-Rao type bound when the dimension $d$ is fixed. It also achieves
Masahito Hayashi
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Asymptotic normality of randomized periodogram for estimating quadratic variation in mixed Brownian–fractional Brownian model

open access: yesModern Stochastics: Theory and Applications, 2015
We study asymptotic normality of the randomized periodogram estimator of quadratic variation in the mixed Brownian–fractional Brownian model. In the semimartingale case, that is, where the Hurst parameter H of the fractional part satisfies $H\in (3/4,1)$,
Ehsan Azmoodeh   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Local Projection-Based Stabilized Mixed Finite Element Methods for Kirchhoff Plate Bending Problems

open access: yesAbstract and Applied Analysis, 2013
Based on stress-deflection variational formulation, we propose a family of local projection-based stabilized mixed finite element methods for Kirchhoff plate bending problems.
Xuehai Huang
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

New Versions of Liu-type Estimator in Weighted and non-weighted Mixed Regression Model

open access: yesمجلة بغداد للعلوم, 2020
This paper considers and proposes new estimators that depend on the sample and on prior information in the case that they either are equally or are not equally important in the model.
Mustafa Ismaeel Naif Alheety
doaj  

Grid Convergence Analysis for MUSCL-based Numerical Scheme in Shockwave-containing Flows

open access: yesMATEC Web of Conferences, 2019
This paper investigated the influence of limiter functions widely utilized in MUSCL-type (Monotone Upstream-centred Schemes for Conservation Laws) upwind numerical schemes on the solution accuracy of shockwave-containing flows.
Li Guangning   +3 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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