Results 71 to 80 of about 1,849 (152)

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, Volume 103, Issue 4, Page 540-566, October 2025.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source

Gonadal surgery in gonadal dysgenesis. clinical case and literature review.

, 2022
Disorders of sexual development are conditions in which sexual development is impaired. The field of disorders of sexual development is constantly evolving, however, common approach is lacking.
Trainavičius, Ignas,
core  

Laparoscopy versus ultrasonography for the evaluation of Müllerian duct remnants in male patients with disorder of sex differentiation

Egyptian Pediatric Association Gazette
Background The diagnosis of male differences of sex development is a challenging multidisciplinary team task, that requires external genital evaluation, karyotyping, hormonal profiling, radiological work up and frequently diagnostic laparoscopy and ...
Mohamed Sayed Abd El-Monsif, Noha Arafa, Mahmoud Marei Marei, Gamal Eltagy, Ahmed M. K. Wishahy   +4 more
doaj   +1 more source

Biology and Management of Male‐Bodied Athletes in Elite Female Sports

Drug Testing and Analysis, Volume 17, Issue 9, Page 1703-1714, September 2025.
Graphical representation of the relationships of transgender and XY DSDF as male‐bodied athletes along the binary dimensions of biological sex. ABSTRACT The physical advantages in elite power sports that allow men to surpass women are derived from the experience of male puberty.
David J. Handelsman, Stéphane Bermon
wiley   +1 more source

Isodicentric Y (p11.32) chromosome in an infant with mixed gonadal dysgenesis

, 2006
Among the structural abnormalities affecting the human Y chromosome, dicentric chromosomes are the most common. A wide spectrum of phenotypes of patients with a dicentric Y chromosome exists, ranging from almost males through mixed gonadal dysgenesis to ...
Aktas, D, Senocak, ME, Gonc, N, Tuncbilek, E, Alikasifoglu, M   +4 more
core   +1 more source

Unexpected finding of an intact distal vagina in an infant with mixed gonadal dysgenesis

, 2011
Mixed gonadal dysgenesis (MGD) is a form of sex chromosome disorder of sex development with large phenotypic variability. Patients with MGD typically have asymmetric and ambiguous genitalia with a combination of Müllerian and Wolffian duct derivatives ...
Rudy Alvarez, Martin N. Kaefer, Alvarez, Rudy, Kaefer, Martin N., Todd D. Nebesio, Erica A. Eugster, Eugster, Erica A., Nebesio, Todd D., Cabrera, Susanne M., Susanne M. Cabrera   +9 more
core   +1 more source

A case of mixed gonadal dysgenesis with structural abnormalities of X chromosome (Xp+) [PDF]

, 1985
An abnormal extra band on the short arm of the X chromosome was found in a 7-year-old reared as a female, of mixed gonadal dysgenesis. She had ambiguous external genitalia, scoliosis, short stature, mental retardation and motor paralysis of the limbs ...
伏見, 登, 渡瀬, 秀樹, 大田黒, 和生, 渡辺, 秀輝   +3 more
core  

A novel SRY mutation leads to asymmetric SOX9 activation and is responsible for mixed 46,XY gonadal dysgenesis

, 2012
SRY, located on the Y chromosome, is one of the key genes involved in human sex determination. SRY mutations are responsible for 10-15% of all cases of 46,XY gonadal dysgenesis (GD) but are rarely implicated in the pathogenesis of mixed ...
Birraux, Jacques Maurice, Morel, Yves, Klee, Philippe, Dahoun, Sophie, Dirlewanger, Mijam, Girardin, Céline, Plotton, Ingrid, Rougemont-Pidoux, Anne-Laure, Bena, Frédérique, Schwitzgebel Luscher, Valérie   +9 more
core   +1 more source

A case of mixed gonadal dysgensis: A diagnostic challenge

Journal of Human Reproductive Sciences, 2019
A 2-year-old child reared as a girl child was brought by parents with ambiguous genitalia noticed since birth. There was no history of failure to thrive or salt-losing crisis.
Uma Kaimal Saikia, Dipti Sarma, Darvin Vamadevan Das, J K Goswami, Kaushik, Chandan Saikia, Abilash Nair   +6 more
doaj   +1 more source

A rare case of mixed gonadal dysgenesis in adulthood: diagnostic delay and unique outcomes. [PDF]

J Surg Case Rep, 2023
Rueangket P, Phansenee S, Laoharojvongsa N, Boonyachan W.   +3 more
europepmc   +1 more source