Results 211 to 220 of about 259,405 (306)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

Generalizing an outbreak cluster detection method for two groups: an application to rabies. [PDF]

R Soc Open Sci
Hayes S, Lushasi K, Changalucha J, Sikana L, Hampson K, Donnelly CA, Nouvellet P.   +6 more
europepmc   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

Preparation and bioactivities of selenium nanoparticles based on a polysaccharide from <i>Dendrobium huoshanense</i>. [PDF]

Front Nutr
Pei Q, Zhang L, Yang Y, Gao C, Ma B, Xi Y, Wang L.   +6 more
europepmc   +1 more source

Mixed modular perverse sheaves on moment graphs [PDF]

, 2017
Shotaro Makisumi
openalex   +1 more source

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Unobtrusive inference of diurnal rhythms from smartphone data. [PDF]

NPJ Digit Med
Knol L, Ross MK, Nagpal A, Burns AP, Morrissey ZD, Hussain F, Eisenlohr-Moul TA, Beckmann CF, Leow A, Marquand AF.   +9 more
europepmc   +1 more source

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

Advanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula, Rosa M. Espinosa‐Marzal   +1 more
wiley   +1 more source

GBS-Assisted Quantum Unsupervised Machine Learning on a Universal Programmable Integrated Quantum Chip. [PDF]

Research (Wash D C)
Zhu H, Luo W, Yan R, Ren C, Guo J, Zhao Z, Ma H, Chen T, Gao F, Kwek LC, Cai H, Wang Y, Yang J, Liu AQ.   +13 more
europepmc   +1 more source

Defect‐Mediated Scintillation in Fully Inorganic Perovskites via Water‐Induced 0D/3D Phase Modulation

Advanced Functional Materials, EarlyView.
A reproducible synthesis to control 3D/0D phase ratios via water‐tuned solvent–antisolvent methods is presented. Enhanced scintillation yield and ultrafast decay are achieved. Defect‐driven emission mechanisms are revealed through cathodoluminescence and radioluminescence, shedding light on the underexplored role of the 0D Cs4PbBr6 and mixed 0D/3D ...
Mario Calora, Francesco Carulli, Nadir Vanni, Antonella Giuri, Elena Ferrari, Matteo Masino, Laura Lazzarini, Francesca Rossi, Gianluca Accorsi, Anna Moliterni, Davide Altamura, Cinzia Giannini, Luca Cappelletti, Gianluca Quarta, Alberto Quaranta, Rosanna Mastria, Anna Paola Caricato, Sergio Brovelli, Aurora Rizzo   +18 more
wiley   +1 more source