Results 211 to 220 of about 3,537,586 (309)

Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models

Advanced Functional Materials, EarlyView.
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen, Sabah Kasmi, Shrinivas Dumbre, Lies Baekens, Elise Seynaeve, Louise Van den Hauwe, Niccolò Cantini, Aello Garantoudi, Filipe Branco Madeira, Alain Marrot, Emma Tuypens, Sofie Seghers, Anna Kuchmiy, Elisabeth Brabants, Bart Vanderborght, Ine Maes, Sarah Vandenberghe, Jessica Filtjens, Alícia Gordún Peiró, Daliya Kancheva, Ayla Debraekeleer, Florence Lambolez, Emily De Lombaerde, Yong Chen, Rafael Miyazawa Martins, Pauline Formaglio, Damya Laoui, Sofie Deschoemaeker, Bruno G. De Geest, Rogerio Amino, Stefaan De Koker   +30 more
wiley   +1 more source

A pilot randomized controlled trial to examine the impact of a therapy dog intervention on loneliness in adult patients hospitalized in a psychiatric unit. [PDF]

Front Psychiatry
Gee NR, Townsend L, Friedmann E, Barker SB, Thakre TP, Mueller MK.   +5 more
europepmc   +1 more source

Mixed modular perverse sheaves on moment graphs [PDF]

, 2017
Shotaro Makisumi
openalex   +1 more source

CRISPR/Cas9‐Assisted Microrobots for Fast and Ultrasensitive “On‐The‐Fly” Next‐Generation DNA Detection

Advanced Functional Materials, EarlyView.
This work presents self‐propelled CRISPR/Cas9‐functionalized Au–MRs for rapid, amplification‐free, “on‐the‐fly” DNA detection. By harnessing motion‐assisted signal recovery, the platform achieved the limit of detection in low fM DNA concentrations, enabling detection across a wide dynamic range within only 5 min, which is significantly faster than any ...
Jyoti, Petr Michálek, Zbyněk Heger, Martin Pumera   +3 more
wiley   +1 more source

GRPhIN: graphlet characterization of regulatory and physical interaction networks. [PDF]

Bioinform Adv
Barelvi A, Anderson O, Ritz A.
europepmc   +1 more source

Transparent Inorganic–Organic Bilayer Neural Electrode Array and Integration to Miniscope System for In Vivo Calcium Imaging and Electrophysiology

Advanced Functional Materials, EarlyView.
This study presents the BioCLEAR system, a highly transparent and conductive neural electrode array composed of silver nanowires (AgNWs) and doped PEDOT:PSS, enabling neural recordings with minimal optical artifacts. When integrated with a GRIN lens, this cost‐effective neural implant allows simultaneous electrophysiological recording and GCaMP6‐based ...
Dongjun Han, Kevin Cheng, Swathy Sampath Kumar, Anil Bollimunta, Elizabeth E. Torr, Juhwan Kim, Kyoungmin Kim, Hyungjun Choi, Seongkwon Hwang, Sarah Brodnick, David Cheng, Lindsay Gray, Yei Hwan Jung, William L. Murphy, Aaron J. Suminski, Jonathan J. Nassi, Justin C. Williams, Dong‐Wook Park   +17 more
wiley   +1 more source

Electrophysiological data showing the acute alcohol effect on neuronal excitability in the murine posterior parietal cortex. [PDF]

Data Brief
Licheri V, Jacquez BJ, Valenzuela CF, Brigman JL.   +3 more
europepmc   +1 more source

Mixed-integer Programming Models and a Cut-generating Method for Solving Semi-cooperative Attack Graph Problems

Phanuel Allaissem Beremadji, R.L. Curry
openalex   +1 more source

Ionic Control of Microstructure and Lubrication in Charged, Physically Cross‐Linked Hydrogels

Advanced Functional Materials, EarlyView.
Here, charged, physically cross‐linked poly(methacrylamide‐co‐methacrylic acid) hydrogels stabilized by a short‐range attractive, long‐range repulsive potential is investigated. This work uncovers how salt addition alters not only swelling, but also the microstructure and dynamics, near‐surface stiffness and charge, and ultimately, its lubricity. Salts
Alexander Deptula, Rosa M. Espinosa‐Marzal   +1 more
wiley   +1 more source

Reticulon-1 synthesis controls outgrowth and microtubule dynamics in injured cortical axons. [PDF]

Life Sci Alliance
Luarte A, Gallardo J, Corvalán D, Chakraborty A, Gouveia Roque C, Bertin F, Contreras C, Ramírez JP, Weber A, Acevedo W, Zuschratter W, Herrera-Molina R, Wyneken Ú, Paula-Lima A, Adasme-Rocha T, Toledo J, Vergara R, Figueroa A, González C, González-Billault C, Hengst U, Couve A.   +21 more
europepmc   +1 more source