Results 211 to 220 of about 4,591,548 (284)

Minor SHIV variants abrogate protective efficacy of broadly neutralizing antibodies in rhesus macaques. [PDF]

Nat Commun
Walker-Sperling VEK, Nkolola J, Liu J, Aid M, Julg B, Seaman MS, Barouch DH.   +6 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Probiotic Combination of <i>Lactiplantibacillus plantarum</i> M1 and <i>Limosilactobacillus reuteri</i> K4 Alleviates Early Weaning-Induced Intestinal Injury in Lambs via Modulation of Oxidative and Inflammatory Pathways. [PDF]

Antioxidants (Basel)
Lu Q, Zhang P, Niu Y, Wang C, Zhang F, Niu J, Zeng W, Chen C, Zhang W.   +8 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Predictors of non-diabetic kidney disease in diabetics: A Saudi Arabian perspective. [PDF]

World J Nephrol
Al-Qurashi SH, Khalil MAM, Mahmood HHK, A Al-Ghamdi R, Alsharif MM, Said Ahmed MA, Alghamdi RMH, Sadagah NM.   +7 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Acute Effects of Different Muscle Contraction Types on Biomechanical and Viscoelastic Properties of the Biceps Brachii Measured with Myotonometry. [PDF]

J Funct Morphol Kinesiol
Szajkowski S, Pasek J, Cieślar G.
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Energy and biomass distribution in soil food webs of temperate and tropical forests. [PDF]

Nat Commun
Potapov AM, Semenyuk I, Bluhm SL, Krashevska V, Kudrin A, Migunova V, Pollierer MM, Rozanova O, Tsurikov SM, Zhou Z, Zuev AG, Zueva AI, Scheu S, Tiunov AV.   +13 more
europepmc   +1 more source