Results 251 to 260 of about 1,978,652 (350)

High Radiological Severity in CRSwNP Is Associated With a Mixed Type 2/Type 3 Epithelial Inflammatory Signature. [PDF]

Laryngoscope Investig Otolaryngol
Xu G, Tian M, Wang K, Fan Y, Sun Y, Liu C.   +5 more
europepmc   +1 more source

The Affordances of the Medium: A Comparative Mixed-Method Study of an On-Site and Online Shared Reading Group for People with Cancer [PDF]

Tine Riis Andersen, Anne Mangen, Frank Hakemulder   +2 more
openalex   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

What works to improve health and digital health literacy in disadvantaged groups: A policy-focused evidence brief. [PDF]

Public Health Pract (Oxf)
Harasgama S, Lunn AD, Lamb D, Gkiouleka A, Painter H, Ghanchi A, Ford J.   +6 more
europepmc   +1 more source

Group Dynamics as a Component of the Clinical Learning Environment: A Mixed Sequential Exploratory Study

Marjolaine Dionne Merlin, Frances Gallagher, Stéphan Lavoie   +2 more
openalex   +2 more sources

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Specimen-specific differences in clinical metagenomic sequencing reporting patterns in hospitalized patients: a single-center retrospective observational study. [PDF]

Front Cell Infect Microbiol
Ren JM, Zhang XY, Liu XP, Pei LH, Jiang WP, Zhang XM, Ding H, Huang JS.   +7 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Telerehabilitation in Community Stroke Services: Mixed Methods Evaluation of Current Practice and Lessons for Sustained Use. [PDF]

J Med Internet Res
Chandler E, Dorer C, Pomeroy VM, Hancock NJ.   +3 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source