Results 41 to 50 of about 1,350,679 (311)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The implications of stakeholders' perceptions of land for sustainable land use management in NE Ghana [PDF]

, 2008
There are negative implications of changes in stakeholders traditional land perceptions for sustainable land use and management in north-east Ghana.
Bugri, John, Glaves, Peter, Ridgway, Robert Broughton   +2 more
core  

Mixing Structure of Land-use

Annals of The Tohoku Geographycal Asocciation, 1976
On the distribution based on a certain areal division in which individual units such as persons or households are antecedently grouped, it is noticeable to be able to distinguish two meanings in the relationships among the distributions: Co-variance and Co-occurrence. The Co-occurrence with small interval is called “Mixing” by the author.The purpose of
openaire   +2 more sources

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Getting to school on your own: the correlates of independence and modes of active school travel

Journal of Asian Architecture and Building Engineering, 2023
Young people’s decreased active and independent travel to schools has prompted many countries to devise various policies, initiatives, and programs to counter the associated health detriments.
Jong Seon Lee, Yunmi Park, Tae-Hyoung Tommy Gim   +2 more
doaj   +1 more source

Land use diversity indices and change of mixed land uses in Iskandar Malaysia from 1980s to 2000s [PDF]

, 2014
Diversity in the context of land use planning refers to as the variety of uses in land use and in land use planning, the success of diversity can be achieved through mixed use development.
Majid, Mohammad Rafee, Wan Kassim, Sharifah Athirah Izyan   +1 more
core  

Mixed Land Use and Obesity: An Empirical Comparison of Alternative Land Use Measures and Geographic Scales [PDF]

The Professional Geographer, 2012
Obesity is a growing epidemic in the United States. Walkable neighborhoods, characterized as having the 3Ds of walkability (population Density, land use Diversity, and pedestrian-friendly Design), have been identified as a potentially promising factor to prevent obesity for their residents.
Ikuho, Yamada, Barbara B, Brown, Ken R, Smith, Cathleen D, Zick, Lori, Kowaleski-Jones, Jessie X, Fan   +5 more
openaire   +2 more sources

Land use mix and physical activity in middle-aged and older adults: a longitudinal study examining changes in land use mix in two Dutch cohorts [PDF]

International Journal of Behavioral Nutrition and Physical Activity, 2020
Abstract BACKGROUNDWith urbanization and aging increasing in coming decades, societies face the challenge of keeping aging populations active. Land use mix (LUM) has been associated with cycling and walking, but whether changes in LUM relate to changes in cycling/walking is less known.
J. Mark Noordzij, M.A. Beenackers, J. Oude Groeniger, E.J. Timmermans, I. Motoc, M. Huisman, F.J. van Lenthe   +6 more
openaire   +4 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source