Results 201 to 210 of about 658,858 (308)

Identification and genomic location of resistance to bacterial leaf streak of barley. [PDF]

Plant Genome
Velasco DD, Shi G, Bruggeman R, Horsley R, Baldwin T, Liu Z.   +5 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Detecting entanglement in high-spin quantum systems via a stacking ensemble of machine learning models. [PDF]

Sci Rep
Abd-Rabbou MY, Zahia AA, Abdallah AM, Gouda AA, Qiao CF.   +4 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Comparative Analysis of Diversification Rates in Clonal and Non-Clonal Flowering Plants. [PDF]

Ecol Lett
Kadyan S, Klimešová J, Dimitrov D, Wang Z, Smyčka J, Herben T.   +5 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Preoperative Decline and Postoperative Recovery of Wearable-Derived Physical Activity over a Four-Year Perioperative Period in Total Knee and Hip Arthroplasty. [PDF]

Sensors (Basel)
Zhang Y, Folarin A, Zhong R, Kim H, Stewart C, Sun S, Dobson RJB.   +6 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Weight trajectories throughout adulthood and prostate cancer incidence, aggressiveness, and death in 258 494 men. [PDF]

J Natl Cancer Inst
da Silva M, Fritz J, Elhakeem A, Jochems SHJ, Sun M, Mboya IB, Häggström C, Wahlström J, Michaëlsson K, Magnusson PKE, Lagerros YT, Lönnberg L, Chabok A, Elmståhl S, Nwaru BI, Kankaanranta H, Hedman L, Backman H, Hägg S, Stattin P, Tilling K, Stocks T.   +21 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source