Results 121 to 130 of about 531,914 (339)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Defining the core proteome of the chloroplast envelope membranes [PDF]

open access: yes, 2013
High-throughput protein localization studies require multiple strategies. Mass spectrometric analysis of defined cellular fractions is one of the complementary approaches to a diverse array of cell biological methods. In recent years, the protein content
Ibrahim, Mohamed   +9 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Highly Stable Luminous "snakes" from CsPbX3 Perovskite Nanocrystals Anchored on Amine-Coated Silica Nanowires [PDF]

open access: yes, 2019
CsPbX3 (X = Cl, Br, and I) perovskite nanocrystals (NCs) are known for their exceptional optoelectronic properties, yet the material's instability toward polar solvents, heat, or UV irradiation greatly limits its further applications.
He, L   +7 more
core  

Review on Blueprint of Designing Anti-Wetting Polymeric Membrane Surfaces for Enhanced Membrane Distillation Performance [PDF]

open access: yes, 2019
Recently, membrane distillation (MD) has emerged as a versatile technology for treating saline water and industrial wastewater. However, the long-term use of MD wets the polymeric membrane and prevents the membrane from working as a semi-permeable ...
Kwon, Young-Nam   +2 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Isolation and characterization of a laminin-binding protein from rat and chick muscle. [PDF]

open access: yes, 1988
A major laminin-binding protein (LBP), distinct from previously described LBPs, has been isolated from chick and rat skeletal muscle (Mr 56,000 and 66,000, respectively).
Frazer, KA   +3 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Uremic Toxins Removal with Mixed Matrix Membranes Adsorbers (mmmas)

open access: yesChemical Engineering Transactions, 2019
Mixed Matrix Membrane Adsorbers (MMMAs) based on Cellulose Acetate (CA) were prepared and tested for the removal of uremic toxins from spent dialysate aqueous streams from hemodialysis treatments. MMMAs were fabricated and modified with a natural zeolite,
Matilde De Pascale   +2 more
doaj   +1 more source

Properties of soliton surfaces associated with integrable $\mathbb{C}P^{N-1}$ sigma models

open access: yes, 2017
We investigate certain properties of $\mathfrak{su}(N)$-valued two-dimensional soliton surfaces associated with the integrable $\mathbb{C}P^{N-1}$ sigma models constructed by the orthogonal rank-one Hermitian projectors, which are defined on the two ...
Dey, Sanjib, Grundland, A. M.
core   +1 more source

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