Results 241 to 250 of about 2,900,458 (300)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Adolescents' Strategies to Manage Mental Health Challenges In and After the Pandemic: Two Mixed-Methods Studies. [PDF]

open access: yesRes Child Adolesc Psychopathol
Huizenga HM   +4 more
europepmc   +1 more source

Feasibility and acceptability of ExerciseGuideUK for those living with and beyond lung cancer: a mixed methods study. [PDF]

open access: yesSupport Care Cancer
Curry J   +6 more
europepmc   +1 more source

Alignment Between Cardiologists and AI-Driven Diagnostic Systems: Mixed Methods Study. [PDF]

open access: yesJ Med Internet Res
Mahdavi M   +5 more
europepmc   +1 more source

Exploring power and influence using a mixed-methods approach

open access: yes, 2012
Power, Exploring   +2 more
core   +1 more source

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