A review of physics-based models in prognostics: application to gears and bearings of rotating machinery [PDF]
, 2016 Health condition monitoring for rotating machinery has been developed for many years due to its potential to reduce the cost of the maintenance operations and increase availability.
Cubillo, Adrian +2 more
core +2 more sources
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Investigation of mixed mode fatigue crack propagation in SEN-specimen under in-phase and out-of-phase conditions due to tension-compression and torsional loading [PDF]
MATEC Web of Conferences, 2019 Numerous cases of damage by fatigue in structures are related to mechanical stresses due to mixed mode loading conditions. To prevent such cases of failure a precise knowledge of the corresponding theoretical background is indispensable.
Koester Paul +2 more
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Some experimental observations of crack-tip mechanics with displacement data [PDF]
, 2015 Estudio de la mecánica en el vértice de la grieta mediante datos de desplazamiento.In the past two decades, crack-tip mechanics has been increasingly studied with full-field techniques.
Lopez-Crespo, Pablo +3 more
core +4 more sources
Extension of the CJP model to mixed mode I and mode II
Fracture and Structural Integrity, 2013 The present authors have previously proposed a novel ‘plastic inclusion’ approach for dealing with the local plasticity which occurs at the tip of a growing fatigue crack.
C. J. Christopher +3 more
doaj
Application of local and non-local approaches to multiple fatigue crack initiation and propagation [PDF]
, 2003 Fatigue strength conditions presented in terms of normalized equivalent stress functionals defined on loading processes are used to unite the stages of material damage with fatigue crack initiation and multiple crack propagation under arbitrary loading ...
Mikhailov, SE, Namestnikova, IV
core
Mixed-Mode Fatigue Characteristics of Composite/Metal Interfaces
Journal of The Korean Society for Composite Materials, 2010 For most of structural failure in engineering structures , fracture often takes place due to a phenomenon called fatigue. Therefore, many studies about the effect of the various mode-mixities on fatigue characteristics have been performed. However, most of the former studies are about metal/metal interface or delamination of composite.
Sang Ho Baek +3 more
openaire +2 more sources
Crack front segmentation under combined mode I - and mode III - loading [PDF]
Fracture and Structural Integrity, 2016 ABSTRACT. This article approaches the topic of crack initiation and crack growth behaviour under combined mode I- and mode III-loading conditions. Such loading combinations especially lead to a crack, which unscrew out of its initial orientation
A. Eberlein , H. A. Richard
doaj +1 more source
, 2019 Most of the existing methods for fatigue-driven delamination are limited to two-dimensional (2D) applications or their predictive capabilities have not been validated in three-dimensional (3D) problems.
Bak, Brian L. V. +6 more
core +1 more source