Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The transformation brought by stress management training based on Bar-On's mixed model of emotional intelligence in nursing students: a qualitative study. [PDF]
BMC NursTek Sevindik S, Mansuroğlu S.
europepmc +1 more source
Multi‐modal imaging, model‐based tracking, and mixed reality visualisation for orthopaedic surgery
, 2017 Sing Chun Lee +7 more
openalex +1 more source
Cross-validation for nonlinear mixed effects models [PDF]
, 2013 Emily Colby, Eric Bair
openalex +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A Mixed Model of Clinical Characteristics, Strain Elastography and ACR-TIRADS Predicts Malignancy in Small Thyroid Nodules: A Prospective Single-Center Study. [PDF]
Medicina (Kaunas)Angelopoulos N +8 more
europepmc +1 more source
Modelling a whole building stock: domestic, non-domestic and mixed use [PDF]
, 2017 Stephen Evans +2 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Levothyroxine Administration Techniques Audit and Utility of its Assessment at Each Visit: A Hospital-based Mixed Model Study. [PDF]
Indian J Endocrinol MetabSingh R, Tandon A.
europepmc +1 more source
Modeling adhesive contacts under mixed-mode loading
, 2019 Mohsen Khajeh Salehani +2 more
openalex +1 more source