Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Improvement of trip generation rates for mixed-use development in Klang Valley, Malaysia. [PDF]
Sci Rep, 2023 Goh BH, Yuen CW, Onn CC.
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Cancelling methyl bromide for postharvest use to trigger mixed economic results
California Agriculture, 1994 The economic impacts of methyl bromide's (MBr) phaseout for postharvest fumigation vary widely among growers and, in the case of fumigation to meet quarantine restrictions, may vary widely from year to year.
C Yarkin +3 more
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Habitat use of and threats to African large carnivores in a mixed-use landscape. [PDF]
Conserv Biol, 2022 Strampelli P +4 more
europepmc +1 more source
Accessibility of Vendor-Created Video Tutorials for People with Disabilities [PDF]
, 2016 Many video, screencast, webinar, or interactive tutorials are created and provided by vendors for use by libraries to instruct users in database searching.
Oud, Joanne
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Identification and prediction of mixed-use functional areas supported by POI data in Jinan City of China. [PDF]
Sci Rep, 2023 Zheng M, Wang H, Shang Y, Zheng X.
europepmc +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Combining Passive Sampling with Suspect and Nontarget Screening to Characterize Organic Micropollutants in Streams Draining Mixed-Use Watersheds. [PDF]
Environ Sci Technol, 2022 Wang S +4 more
europepmc +1 more source