Results 131 to 140 of about 6,397,633 (296)

A note on the implementation of the BFC-MSMIP algorithm in C++ by using COIN-OR as an optimization engine [PDF]

The aim of this technical report is to present some detailed explanations in order to help to understand and use the algorithm Branch and Fix Coordination for solving MultiStage Mixed Integer Problems (BFC- MSMIP).
Escudero Bueno, Laureano F., Garín Martín, María Araceli, Merino Maestre, María, Pérez Sainz de Rozas, Gloria   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Predicting Parasite Dynamics in Mixed-Use Trans-Himalayan Pastures to Underpin Management of Cross-Transmission Between Livestock and Bharal. [PDF]

Front Vet Sci, 2021
Khanyari M, Suryawanshi KR, Milner-Gulland EJ, Dickinson E, Khara A, Rana RS, Rose Vineer H, Morgan ER.   +7 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Human Fecal Pollution Monitoring and Microbial Risk Assessment for Water Reuse Potential in a Coastal Industrial-Residential Mixed-Use Watershed. [PDF]

Front Microbiol, 2021
Kongprajug A, Denpetkul T, Chyerochana N, Mongkolsuk S, Sirikanchana K.   +4 more
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Evaluating the challenges and impacts of mixed-use neighborhoods on urban planning: an empirical study of a megacity, Karachi, Pakistan

Discover Sustainability
Introduction Modern development is patented by rapid urbanization, which largely negatively affects the quality of life. Over the past few decades in the World; in the field of urban planning and the real estate market, Mixed-use development has become a
Anila Kausar, Salman Zubair, Hadeeqa Sohail, Muhammad Mushahid Anwar, Asad Aziz, Sergij Vambol, Viola Vambol, Nadeem A. Khan, Serhii Poteriaiko, Vasyl Tyshchenko, Rustam Murasov, Fizza Ejaz, Owais Iqbal Khan   +12 more
doaj   +1 more source

Monitoring Benzene, Toluene, Ethylbenzene, and Xylene (BTEX) Levels in Mixed-Use Residential-Commercial Buildings in Shiraz, Iran: Assessing the Carcinogenicity and Non-Carcinogenicity Risk of Their Inhabitants. [PDF]

Int J Environ Res Public Health, 2022
Baberi Z, Azhdarpoor A, Hoseini M, Baghapour M, Derakhshan Z, Giannakis S.   +5 more
europepmc   +1 more source

Mixing of Land-use

Studies in Regional Science, 1976
The remarkable aspect of urbanization in Japan is the rapid change of landuse, which is due to enlarging of urbanized area and renewing of city. The development of such change is almost never planned and is not uniformly and continuously carried out.
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source