Results 51 to 60 of about 6,390,979 (296)

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source

Course and outcome of patients with alcohol use disorders following an alcohol intervention during hospital attendance: mixed method study

BJPsych Open, 2021
Background Alcohol-related presentations to acute hospitals in the UK are increasing, but little is known of the clinical characteristics or natural history of this patient group.
Sophia E. Chambers, David S. Baldwin, Julia M. A. Sinclair   +2 more
doaj   +1 more source

Implementing Mixed Land Use Rooting Jane Jacobs' Concept of Diversity in Urban Sustainability [PDF]

, 2017
Nowadays, sustainability has become an important issue in any development project, including area development. Thishappen because the area development requires space, in this case land. As people developing land, it damages theenvironment. It means there
bramiana, C. N. (chely), Harsritanto, B. I. (Bangun), Widiastuti, R. (Ratih)   +2 more
core  

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

New Church Typologies: Innovative Relationships between Churches and Cities in Germany

In_Bo
Rapid demographic change and the ongoing process of dechurching are bringing about significant transformations in Germany’s sacred building landscape. Strategies for managing churches no longer in regular liturgical use vary considerably.
Albert Gerhards
doaj   +1 more source

Mix-ORAM

Proceedings of the 2017 on Workshop on Privacy in the Electronic Society, 2017
Oblivious RAM (ORAM) is a key technology for providing private storage and querying on untrusted machines but is commonly seen as impractical due to the high overhead of the re-randomization, called the eviction, the client incurs. We propose in this work to securely delegate the eviction to semi-trusted third parties to enable any client to accede the
Toledo, Raphael R., Danezis, George, Echizen, Isao   +2 more
openaire   +2 more sources

Mixed methods in health care research. Paradigms and philosphy [PDF]

, 2018
When to use mixed methods is one of the most challenging issues that health care researchers currently face. The predominance of quantitative methods have not been enough to respond to many relevant questions on health care, that need a multiple approach.
Kendall, Sally
core  

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

A power-based perspective of mechanical systems [PDF]

, 2005
This paper is concerned with the construction of a power-based modeling framework for a large class of mechanical systems. Mathematically this is formalized by proving that every standard mechanical system (with or without dissipation) can be written as ...
Jeltsema, D.,, Scherpen, J. M. A.,
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source