Results 71 to 80 of about 6,390,979 (296)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Geometric uncertainty relation for mixed quantum states

open access: yes, 2014
In this paper we use symplectic reduction in an Uhlmann bundle to construct a principal fiber bundle over a general space of unitarily equivalent mixed quantum states.
Andersson, Ole, Heydari, Hoshang
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Spatial distribution of Urban land-use in Addis Ababa, Ethiopia

open access: yesUrban, Planning and Transport Research
This study underlines the critical function of efficient urban land use planning, recommending mixed land use for improved city sustainability. The research, which is rooted in the historical context of urban renewal, attempts to harmonize theoretical ...
Girmachew Tariku Jinollo   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Quantum teleportation using non-orthogonal entangled channels

open access: yes, 2010
We study quantum teleportation with the resource of non-orthogonal qubit states. We first extend the standard teleportation protocol to the case of such states. We investigate how the loss of teleportation fidelity resulting for the use of non-orthogonal
A K Pan   +11 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Felipe Ángeles Fire Station. 2021-22 Tutitlán de Mariano Escobedo, Mexico

open access: yesARQ
In a municipality shaped by industrial tradition and peripheral urbanization, the Felipe Ángeles Fire Station is introduced as both public infrastructure and collective space.
Departamento del Distrito   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Impact of Built Environment on Mixed Land Use: Evidence from Xi’an

open access: yesLand
Mixed land use is recognized as a crucial strategy for enhancing urban vitality and promoting urban renewal. While existing research has mainly focused on measuring mixed land use along single dimensions, there remains a notable gap in studies that ...
Jianwei Li   +3 more
doaj   +1 more source

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