Results 181 to 190 of about 301,664 (295)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Static Mixers for High-Viscosity Systems: From Classical Helices to Machine-Learning-Optimized Geometries. [PDF]

ACS Omega
Luo S, Wang C.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Formulation of Personalized, Fortified Beverage Nanoemulsions for Space Exploration with Omega‑3 Polyunsaturated Fatty Acids. [PDF]

ACS Food Sci Technol
Schmidt S, Fisk ID, Yang N, Saarela M, Hessel V.   +4 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1. [PDF]

Commun Chem
Doppler D, Grieco A, Koh D, Manna A, Ansari A, Alvarez R, Karpos K, Le H, Sonker M, Ketawala GK, Mahmud S, Quereda-Moraleda I, Sen S, Pey AL, Letrun R, Dörner K, Koliyadu JCP, de Wijn R, Bielecki J, Han H, Kim C, Koua FHM, Round A, Sarma A, Sato T, Schmidt C, Vakili M, Zabelskii D, Bean R, Mancuso AP, Schulz J, Fromme R, Medina M, Grant TD, Fromme P, Kirian RA, Botha S, Manuel Martin-Garcia J, Ros A.   +38 more
europepmc   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Terahertz-range on-chip local oscillator based on Josephson junction arrays for superconducting quantum-limited receivers. [PDF]

Beilstein J Nanotechnol
Khan FV, Filippenko LV, Ermakov AB, Fominsky MY, Koshelets VP.   +4 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Distinct metabolic signatures of Alzheimer's and Parkinson's disease revealed through genetic overlap. [PDF]

EBioMedicine
Stinson SE, Shadrin AA, Rahman Z, Rødevand L, Broce IJ, Selbæk G, Stefansson H, Haavik J, Parker N, Koch E, Frei O, O'Connell KS, Smeland OB, Djurovic S, Dale AM, van der Meer D, Andreassen OA.   +16 more
europepmc   +1 more source