Results 181 to 190 of about 986,782 (318)

Study of mixing in swirling turbulent jets

open access: yes, 2002
Large Eddy Simulation of swirling flows in a typical gas turbine burner has been carried out. The goal has been to study the effects of swirl number, inlet velocity profile, confining wall distance, Reynolds- and Schmidt-number effects on the flow and ...
Szász, Robert-Zoltán,   +3 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Development of Brown-Roshko structures in the mixing layer behind a splitter plate

open access: yes, 2008
A direct numerical simulation has been performed of the near field of a mixing layer formed between a high-speed turbulent stream and a low-speed laminar stream. For improved realism, the simulation includes the splitter plate in the computational domain.
Sandberg, Richard D., Sandham, Neil D.
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Atomistic insight into Al-Mg friction stir welding process via molecular dynamics simulation. [PDF]

open access: yesPLoS One
Nguyen VT   +5 more
europepmc   +1 more source

Forests : to mix or not to mix

open access: yes, 1992
La sylviculture,dans nos régions tempérées en particulier, a évolué vers une simplification des écosystèmes forestiers, une rationalisation progressive de la conduite des peuplements, en vue d'établir une prévision fiable des récoltes et une planification économique des opérations forestières.
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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