Results 21 to 30 of about 669,263 (219)

Siphon-Induced Droplet Break-Off for Enhanced Mixing on a Centrifugal Platform

Inventions, 2019
We present a powerful and compact batch-mode mixing and dilution technique for centrifugal microfluidic platforms. Siphon structures are designed to discretize continuous flows into a sequence of droplets of volumes as low as 100 nL.
Robert Burger, David J Kinahan, Hélène Cayron, Nuno Reis, João Fonseca, Jens Ducrée   +5 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

A Scalable Dynamic Cascade Flow Reactor for Challenging Continuous Heterogeneous Processes

CHIMIA
Continuous processes (often referred to as flow chemistry) offers multiple advantages over batch processes and are of particular interest for industrial applications as they provide a more direct path towards process intensification, increased safety and
Kim-Long Diep, Emilie Buchs, Marlies Moser, Finn L. Steinemann, Alain G. Georg, Flavien L. Morel, Michal Dabros, Roger Marti   +7 more
doaj   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

An Integrated Pumping and Mixing Device

Journal of Fluid Science and Technology, 2011
The present work numerically characterizes a microfluidic device with pumping and mixing functions for lab-on-a- chip applications. The planar fluidic network of the device consists of two inlet channels, a pump chamber, a neck channel, and an outlet ...
Thien X. DINH, Yoshifumi OGAMI
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Scale‐Up Strategy Focused on Hydrodynamic Stress for Mammalian Cell Culture Established by a Dry‐Wet Approach

Engineering in Life Sciences
Today, most recombinant protein drugs are produced by mammalian cells in a stirred‐type bioreactor (BR). Although cell culture scale‐up strategies have been extensively investigated, scale‐up and switching BRs while maintaining comparable culture ...
Hiroyuki Kenmoku, Akira Kaneko, Takanobu Saito, Takahiro Nemoto, Yoshikazu Kato, Shunsuke Ohira   +5 more
doaj   +1 more source

Concentration measurement in a planar liquid jet with a chemical reaction by using the improved concentration measurement system based on the light absorption spectrometric method

Journal of Fluid Science and Technology, 2014
We improve a spatial resolution of concentration measurement system based on the light absorption spectrometric method, which is used to measure instantaneous concentrations of multiple absorptive species.
Takahiro NAITO, Tomoaki WATANABE, Yasuhiko SAKAI, Kouji NAGATA, Yasumasa ITO   +4 more
doaj   +1 more source

Air entrainment and pressure drop in low-cost ejectors [PDF]

Anais da Academia Brasileira de Ciências, 2020
This study investigated experimentally the air entrainment and pressure drop in low-cost ejectors composed of two pieces shaped from PVC bars inserted in a 25 mm T-junction of the same material.
DANIEL D. LIMA, IRAN E. LIMA NETO
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source