Results 101 to 110 of about 876,676 (294)

Quantifying the effect of mixing on the mean age of air in CCMVal-2 and CCMI-1 models [PDF]

open access: yesAtmospheric Chemistry and Physics, 2018
The stratospheric age of air (AoA) is a useful measure of the overall capabilities of a general circulation model (GCM) to simulate stratospheric transport.
S. Dietmüller   +28 more
doaj   +1 more source

Four-wave mixing and generation of terahertz radiation in an alternating-strain coupled quantum-well structure [PDF]

open access: yes, 1996
We propose a scheme for exciting steady-state tunneling oscillations of an electronic wave packet in a semiconductor coupled quantum-well structure with strain of the opposite polarity in the two wells. A detailed study of the four-wave mixing process in
Paiella, Roberto, Vahala, Kerry J.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Mixing efficiency in heterodyne systems [PDF]

open access: yes
How the spatial distributions of the signal and local oscillator fields affect the heterodyne signal to noise ratio is examined for both a single detector and an array of detectors. For an array, the distribution of gain among the intermediate frequency (
Fink, D.
core   +1 more source

Four-Wave mixing in degenerate Fermi gases: Beyond the undepleted pump approximation

open access: yes, 2003
We analyze the full nonlinear dynamics of the four-wave mixing between an incident beam of fermions and a fermionic density grating. We find that when the number of atoms in the beam is comparable to the number of atoms forming the grating, the dephasing
A.G. Rojo   +26 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Importance mixing: Improving sample reuse in evolutionary policy search methods

open access: yes, 2018
Deep neuroevolution, that is evolutionary policy search methods based on deep neural networks, have recently emerged as a competitor to deep reinforcement learning algorithms due to their better parallelization capabilities.
Perrin, Nicolas   +2 more
core  

Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles. [PDF]

open access: yes, 2015
Flaviviruses deliver their RNA genome into the host-cell cytoplasm by fusing their lipid envelope with a cellular membrane. Expression of the flavivirus pre-membrane and envelope glycoprotein genes in the absence of other viral genes results in the ...

core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Enhancing Microfluidic Systems’ Mixing Efficiency Using Design Models with Convergent–Divergent Sinusoidal Microchannel Walls: Experimental Investigations Based on Entropy Minimization Flow Structures

open access: yesEngineering Proceedings
This study presents an innovative passive micromixer design featuring convergent–divergent sinusoidal walls, evaluated using the Villermaux–Dushman protocol.
Kingsley Safo   +2 more
doaj   +1 more source

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