Results 71 to 80 of about 865,428 (296)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In the context of space exploration, electrowetting-on-dielectric (EWOD) microfluidic systems hold substantial promise for enhancing in-situ analysis and experimentation, particularly given its potential for precise control of fluid dynamics in the ...
Yaming Wei +7 more
doaj +1 more source
THE STUDY OF THE KINETICS OF THE MIXING PROCESS THE RAW FISH AND PLANT COMPONENTS
The article is devoted to the study of kinetics and analysis of the regularity of the process of mixing offish raw materials and vegetable component to obtain a minced mixture in the technology of frozen semi-finished products, since the introduction of ...
Albert Hamed-Harisovich Nugmanov +2 more
doaj
Comparative Analysis of Passive Micromixers at a Wide Range of Reynolds Numbers
Two novel passive micromixers, denoted as the Y-Y mixer and the H-C mixer, based on split-and-recombine (SAR) principle are studied both experimentally and numerically over Reynolds numbers ranging from 1 to 100.
Vladimir Viktorov +2 more
doaj +1 more source
Thermohaline mixing and the photospheric composition of low-mass giant stars [PDF]
We compute full evolutionary sequences of red giant branch stars close to the luminosity bump by including state of the art composition transport prescriptions for the thermohaline mixing regimes. In particular we adopt a self-consistent double-diffusive
Althaus +33 more
core +4 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Protein refolding in an oscillatory flow reactor [PDF]
We demonstrate that an oscillatory flow reactor is a viable reactor for protein refolding via direct dilution. The mixing characteristics of the oscillatory flow reactor are well described and controllable and, importantly, can be scaled-up to ...
Lee, CT +3 more
core

