Results 71 to 80 of about 865,428 (296)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Enhancing Micro-Droplet Mixing in Microfluidic Systems Via Electrowetting-Induced Parametric Oscillations

open access: yesAerospace Research Communications
In the context of space exploration, electrowetting-on-dielectric (EWOD) microfluidic systems hold substantial promise for enhancing in-situ analysis and experimentation, particularly given its potential for precise control of fluid dynamics in the ...
Yaming Wei   +7 more
doaj   +1 more source

THE STUDY OF THE KINETICS OF THE MIXING PROCESS THE RAW FISH AND PLANT COMPONENTS

open access: yesСовременная наука и инновации, 2022
The article is devoted to the study of kinetics and analysis of the regularity of the process of mixing offish raw materials and vegetable component to obtain a minced mixture in the technology of frozen semi-finished products, since the introduction of ...
Albert Hamed-Harisovich Nugmanov   +2 more
doaj  

Comparative Analysis of Passive Micromixers at a Wide Range of Reynolds Numbers

open access: yesMicromachines, 2015
Two novel passive micromixers, denoted as the Y-Y mixer and the H-C mixer, based on split-and-recombine (SAR) principle are studied both experimentally and numerically over Reynolds numbers ranging from 1 to 100.
Vladimir Viktorov   +2 more
doaj   +1 more source

Thermohaline mixing and the photospheric composition of low-mass giant stars [PDF]

open access: yes, 2011
We compute full evolutionary sequences of red giant branch stars close to the luminosity bump by including state of the art composition transport prescriptions for the thermohaline mixing regimes. In particular we adopt a self-consistent double-diffusive
Althaus   +33 more
core   +4 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Protein refolding in an oscillatory flow reactor [PDF]

open access: yes, 2001
We demonstrate that an oscillatory flow reactor is a viable reactor for protein refolding via direct dilution. The mixing characteristics of the oscillatory flow reactor are well described and controllable and, importantly, can be scaled-up to ...
Lee, CT   +3 more
core  

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