Results 191 to 200 of about 706,749 (345)

STUDY ON THE INFLUENCE OF THE MIX DESIGN OF FRESH CONCRETE TO THE RHEOLOGY INDEX BY USING THE INCLINED FLOW TEST APPARATUS

, 2013
Hiroyuki Sasakura, Yoshihiro Masuda, Young-Ran Lee   +2 more
openalex   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Influence of impeller configuration and operating parameters on granular mixing: a DEM investigation. [PDF]

Sci Rep
Zhou ZH, Zhang Q, Liu Y, Yang XH, Ali KAM, Darwish EA, Xu MZ, Wu LH, Elsaadawi YF, Shousha ER.   +9 more
europepmc   +1 more source

Quantifying errors in the aerosol mixing-state index based on limited particle sample size [PDF]

, 2020
Jessica Gasparik, Qing Ye, Jeffrey H. Curtis, Albert A. Presto, Neil M. Donahue, Ryan C. Sullivan, Matthew West, Nicole Riemer   +7 more
openalex   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Characterization of Binder Interactions in Recycled Hot-Mix Asphalt Mixtures: Blending and Diffusion of Aged and Virgin Asphalt During Mixing and Stockpiling. [PDF]

Materials (Basel)
Yao Y, Cao S, Yang J, Gao J, Xu J, Liu J.   +5 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Performance analysis of a three-dimensional micromixer with baffles using a flexible physics-informed neural network. [PDF]

Sci Rep
Hassanzadeh M, Ghaderi E, Bijarchi MA.
europepmc   +1 more source

INSIGHTS INTO THE RELATIONSHIP BETWEEN MIXING DURATION AND VOLCANIC EXPLOSIVITY INDEX (VEI): PACAYA AND FUEGO VOLCANOES, GUATEMALA

, 2015
Nicola Mari
openalex   +2 more sources