Results 121 to 130 of about 2,142,070 (351)

Modelling shock-induced instabilities, transition and turbulent mixing using high-order methods [PDF]

open access: yes, 2008
High-order numerical methods have been considered and implemented in order to assess their applicability in a range of complex ows centering on shockinduced turbulent mixing.
Mosedale, Andrew Daniel
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Steady streaming: A key mixing mechanism in low-Reynolds-number acinar flows

open access: yes, 2011
Copyright 2011 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Physics of Fluids 23(4):21
Merryn H. Tawhai   +7 more
core   +1 more source

Effect of Mixing Time by Mix Truck on the Physical Properties of Lightweight Air-mixed Soil

open access: yesJournal of the Korean Geoenvironmental Society, 2015
As the physical and mechanical properties of lightweight air-mixed soil change in the procedure of transportation of mix truck, it is necessary to assure whether the properties during construction satisfy those in design. In this study, variations of properties of mixed soil after transportation by mix truck are proved by field test.
Taehyo Kim, Nayoung Kim, Jongchul Im
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Neutrino physics with JUNO [PDF]

open access: yes, 2017
The Jiangmen Underground Neutrino Observatory (JUNO), a 20 kton multi-purpose underground liquid scintillator detector, was proposed with the determination of the neutrino mass hierarchy (MH) as a primary physics goal. The excellent energy resolution and
Conrad, Janet Marie
core   +1 more source

Oblique corrections in general dark U(1) models

open access: yesJournal of High Energy Physics
We investigate the impact of dark Abelian gauge bosons on the electroweak precision measurements at the one-loop level. The dark gauge boson couples to the standard model fermions generally via two kinds of mixing with the electroweak gauge bosons: the ...
Cheng-Wei Chiang, Kazuki Enomoto
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Self-Mixing Diode Laser Interferometry

open access: yes, 2010
Self-mixing interferometry in a laser diode is a very powerful tool in measurement science. The Self-mixing interferometer is a very robust and low cost interferometer with extreme simplicity in alignment and setup.
Shrestha, Pawan Kumar
core  

Generalised CP and A4 family symmetry

open access: yes, 2013
We perform a comprehensive study of family symmetry models based on A4 combined with the generalised CP symmetry H CP. We investigate the lepton mixing parameters which can be obtained from the original symmetry A4 ?
Stuart, Alexander J.   +2 more
core   +1 more source

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