Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Copper Nanoclusters with Exposed Active Sites for Highly Efficient Protoboration of C-C Multiple Bonds. [PDF]
Zhang S, Wen S.
europepmc +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Sustainable biocatalysis <i>via</i> lipase immobilization: pyrolyzed lignocellulosic bamboo supports in batch and continuous flow systems. [PDF]
Albonetti G +7 more
europepmc +1 more source
A Stereoconvergent Annulation in the Synthesis of Lysergic Acid. [PDF]
Firestone ZD, Harbit RC, Smith JM.
europepmc +1 more source
Synthesis and Stereochemical Assignment of Diastereomeric Steroidal Spiro-1,2,4-trioxolanes with Sitostanone Motif Using PLS2 Chemometric Analysis of DFT-Calculated and Experimental <sup>13</sup>C NMR Data. [PDF]
Lobov A +5 more
europepmc +1 more source
Fourier-based chemometric resolution of the FOLFOX regimen through digital filtering with poly-metric sustainability assessment. [PDF]
Maher HM +3 more
europepmc +1 more source

