Results 121 to 130 of about 787,328 (218)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Predictive mixture design of three essential oil blends to enhance antioxidant and antimicrobial activity for food security and nutrition. [PDF]

open access: yesSci Rep
Nacer-Eddine DK   +15 more
europepmc   +1 more source

Application of a Simplex-Centroid Mixture Design to Evaluate the Phenolic Compound Content and Antioxidant Potential of Plants Grown in Mexico. [PDF]

open access: yesFoods, 2023
Navarro-Cortez RO   +4 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

The Use of D-Optimal Mixture Design in Optimizing Formulation of a Nutraceutical Hard Candy. [PDF]

open access: yesInt J Food Sci, 2023
Souiy Z   +7 more
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Optimization of Microbial Consortium Formulation for Oily Food Waste Composting Using Mixture Design Methodology. [PDF]

open access: yesMicroorganisms
Zhang Y   +8 more
europepmc   +1 more source

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