Results 41 to 50 of about 822,611 (252)

Expectation-Maximization-Maximization: A Feasible MLE Algorithm for the Three-Parameter Logistic Model Based on a Mixture Modeling Reformulation

open access: yesFrontiers in Psychology, 2018
Stable maximum likelihood estimation (MLE) of item parameters in 3PLM with a modest sample size remains a challenge. The current study presents a mixture-modeling approach to 3PLM based on which a feasible Expectation-Maximization-Maximization (EMM) MLE ...
Chanjin Zheng   +4 more
doaj   +1 more source

Identifiability of multivariate logistic mixture models [PDF]

open access: yes, 2014
Mixture models have been widely used in modeling of continuous observations. For the possibility to estimate the parameters of a mixture model consistently on the basis of observations from the mixture, identifiability is a necessary condition.
Han, JiQing, Shi, ZiQiang, Zheng, TieRan
core  

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy   +5 more
wiley   +1 more source

Joint effects of prenatal PM2.5 and heavy metals on preterm birth: evidence from a nested case–control study in China

open access: yesFrontiers in Public Health
BackgroundPreterm birth (PTB) is a global health concern. The combined effects of prenatal PM2.5 and heavy metal exposures on PTB risk remain unclear.MethodsA nested case-control study included 111 PTB cases and 124 controls from Chongqing.
Jinxiu Feng   +31 more
doaj   +1 more source

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig   +13 more
wiley   +1 more source

Latent Profiles of Seminary Students’ Perceptions of Sense of Community Amidst the COVID-19 Pandemic

open access: yesReligions
Existing research on sense of community in educational contexts shows positive associations with well-being and negative associations with mental health symptoms. However, exploration of students’ sense of community within the seminary context is minimal.
Peter J. Jankowski   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Learning the dynamics of articulated tracked vehicles [PDF]

open access: yes, 2016
In this work, we present a Bayesian non-parametric approach to model the motion control of ATVs. The motion control model is based on a Dirichlet Process-Gaussian Process (DP-GP) mixture model.
Gianni, Mario   +2 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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