Results 61 to 70 of about 11,920 (267)

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

PREFERENSI KONSUMEN TERHADAP PRODUK HASIL LAUT (STUDI KASUS RESTORAN SEAFOOD MJM KOTA PALU, SULAWESI TENGAH) [PDF]

, 2016
Many bussinessman develop the restaurant of seafood in the Palu Town, Central Sulawesi. The production’s fisheries activities yielded high protein products and consumed by community, not only limited to fisheries products but also the processed product ...
Gazali, Mohamad
core   +1 more source

Robust Stitching Interface and Deep Learning Empowered Hydrogel Human‐Machine Interface

Advanced Science, EarlyView.
A molecular design strategy is presented that exploits synergistic carboxylate anion–quaternary ammonium interactions to simultaneously strengthen the hydrogel–PET interface and the bulk hydrogel network. Integrated with deep learning signal processing, the stable hydrogel–PET interface enables consistent signal acquisition and reliable human‐machine ...
Hao Dong, Yiming Luo, Chuanliu Liu, Mahamood Modupe Rasheedat, Wenjiayi Tan, Fangyu Zhao, Yixue Zhang, Chris Connor, Hua Hou, Hamdy Khamees Thabet, Ben Bin Xu, Huige Wei   +11 more
wiley   +1 more source

Noninvasive unipolar electrogram T-wave upslope is an accurate marker of local refractoriness in explanted hearts with drug-induced repolarization dispersion

, 2022
Background: The relationship between T-wave morphology in local unipolar electrograms (UEGs) as mapped with noninvasive electrocar-diographic imaging (ECGI) and local repolarization time (RT) has not been validated in pronounced RT ...
STOKS, Job, Bear, L, Volders, PGA, Cluitmans, MJM   +3 more
core   +1 more source

Evaluation of Temperature-Based Empirical Models and Machine Learning Techniques to Estimate Daily Global Solar Radiation at Biratnagar Airport, Nepal

Advances in Meteorology, 2020
Global solar radiation (GSR) is a critical variable for designing photovoltaic cells, solar furnaces, solar collectors, and other passive solar applications.
Sandeep Dhakal, Yogesh Gautam, Aayush Bhattarai   +2 more
doaj   +1 more source

Stable Magnetic Nanodomains Engineered Via Ga+‐ion Irradiation For Deterministic Sequential Switching

Advanced Electronic Materials, EarlyView.
Tiny magnetic regions separated by domain walls can store data, but controlling them precisely is difficult. We use focused ion beams to create nanoscale “anisotropy wells” that pin these walls from both sides. This bidirectional pinning holds domains stable in either direction, even with no field applied.
Gijs W.A. Simons, Rik F.J. van Haren, Bert Koopmans   +2 more
wiley   +1 more source

Tolerance Analysis of 3d-MJM parts according to IT grade

IOP Conference Series: Materials Science and Engineering, 2016
In this study we investigate the dimensional accuracy of 3D printed objects and define the International Tolerance (IT) Grade for the linear sizes of parallel opposite surfaces and the diameter of a cylinder. Eight (8) exact parts were printed by an Objet Eden250 3D printer using the Multi Jet Modelling (MJM) process.
K Kitsakis, J Kechagias, N Vaxevanidis, D Giagkopoulos   +3 more
openaire   +1 more source

Real‐World Outcomes of Midostaurin Plus Intensive Chemotherapy in FLT3‐Mutated AML: The PETHRATIFY Study

American Journal of Hematology, EarlyView.
ABSTRACT Mutations in FLT3 are present in approximately 30% of patients with AML. The addition of midostaurin (MIDO) to intensive chemotherapy (IC) became standard of care following the RATIFY trial, but comprehensive real‐world data spanning the full adult age spectrum and including both FLT3‐ITD and FLT3‐TKD mutations remain limited.
Mónica Alejandra Romero Riquelme, Gaspar Aspas Requena, Pilar Lloret‐Madrid, Cristina Gil, Eliana Aguiar, Mar Tormo, Teresa del Bernal del Castillo, Eduardo Rodríguez Arbolí, Josefina Serrano, Joaquín Sánchez‐García, Carlos Rodríguez‐Medina, José Mário Mariz, Rosa Ayala, Joaquín Martínez‐López, María Luz Amigo, Susana Vives, Lorenzo Algarra Algarra, Raimundo García Boyero, Joana Brioso, Tamara Castaño, Juan M. Bergua Burgués, Olga Salamero, María Francisca Bass Maturana, Mercedes Colorado, María García Fortes, María José Sayas Lloris, Belén Vidriales Vicente, Carmen Chillón, Esther Pérez Santaolalla, María Dolores Madrigal, Jorge Labrador Gómez, María José García Pérez, Soledad Casado Calderón, Manuel Pérez Encinas, Amaia Balerdi Malcorra, María Solé Rodríguez, Lara María Gómez García, Pilar Herrera Puente, Olga Arce Fernández, Manuel Barrios García, Víctor Noriega, Rosa Fernández, Mamen Mateos, Carolina Lacalzada, Ágata Almela Gallego, María Carmen García Garay, Carmen Couto, José Antonio Pérez‐Simón, Eva Barragán González, Pau Montesinos   +49 more
wiley   +1 more source

MHD Maxwell Hybrid Nanofluid Transport Featuring Solar Radiation and Thermo‐Diffusive Impacts Over a Permeable Slanted Stretching Sheet

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Hybrid nanofluids have emerged as next‐generation working fluids for advanced engineering application due to their superior heat transport capability in relation to the conventional nanofluids. Motivated by the rising demand for accurate prediction of transport phenomena under realistic operating situations, the present study examines the ...
B. Prabhakar Reddy, Swatmaram, Jumanne Mng'ang'a, Jason M. Mkenyeleye   +3 more
wiley   +1 more source

Moterų ir vyrų kelio tiesiamųjų ir lenkiamųjų raumenų susitraukimo funkcijos priklausomybė nuo temperatūros

Baltic Journal of Sport and Health Sciences, 2018
Tyrimo tikslas — nustatyti vyrų ir moterų kelio tiesiamųjų ir lenkiamųjų raumenų susitraukimo funkcijos priklau- somybę nuo temperatūros. Tiriamųjų kontingentą sudarė 19—23 m. moterys (n = 10) (ūgis — 166,4 ± 5,6 cm; kūno masė — 56,2 ± 6,1 kg) ir vyrai (
Irina Ramanauskienė, Albertas Skurvydas, Marius Brazaitis, Vitas Linonis, Laura Daniusevičiūtė, Mindaugas Dubosas   +5 more
doaj   +1 more source