Results 91 to 100 of about 5,476,619 (222)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Review on Internet Traffic Classification Based on Artificial Intelligence Techniques
International Journal of Information and Communication Technology Research, 2022 Almost every industry has revolutionized with Artificial Intelligence. The telecommunication industry is one of them to improve customers' Quality of Services and Quality of Experience by enhancing networking infrastructure capabilities which could lead ...
Mohammad Pooya Malek +2 more
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
International Journal of General Medicine, 2023 Binyam Tariku Seboka, Delelegn Emwodew Yehualashet, Getanew Aschalew Tesfa School of Public Health, Dilla University, Dilla, EthiopiaCorrespondence: Binyam Tariku Seboka, School of public health, Dilla University, P.O Box: 419, Dilla University, Dilla ...
Seboka BT, Yehualashet DE, Tesfa GA
doaj
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Journal of Inflammation ResearchXin Qiu,1,2,* Shuang Shen,1,* Donghong Lu,2 Nizhen Jiang,3 Yifei Feng,3 Jindu Li,1 Chenglei Yang,1 Bangde Xiang1,4,5 1Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, People’s Republic of China ...
Qiu X +7 more
doaj
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Bollettino del CILEA, 2007 Codex[ml] integrated system has been developed by CILEA with the aim of meeting management, storage and fruition requirements of digital objects. Using Codex[ml] every agency and every library that deals with organ¬ized information can offer the fruition of its own works, text or archives, through an on-line navigation based on different xml metadata ...
Perelli, Matteo, Zini, Carla
openaire +1 more source