Safety and Use of MLC601/MLC901 (NeuroAiDTM) in Primary Intracerebral Hemorrhage: A Cohort Study from the NeuroAiD Safe Treatment Registry [PDF]
Brain Sciences, 2020 Background: MLC601/MLC901 (NeuroAiD™) is a combination of natural products shown to be safe and to aid neurological recovery after brain injuries, especially ischemic stroke. Few studies have investigated NeuroAiD in primary intracerebral hemorrhage (ICH)
Ramesh Kumar +9 more
doaj +5 more sources
MLC901 (NeuroAiD II™) for cognition after traumatic brain injury: a pilot randomized clinical trial. [PDF]
Eur J Neurol, 2018 Background and purpose Treatments to facilitate recovery after traumatic brain injury (TBI) are urgently needed. We conducted a 9‐month pilot, randomized placebo‐controlled clinical trial to examine the safety and potential effects of the herbal supplement MLC901 (NeuroAiD II™) on cognitive functioning following TBI.
Theadom A +5 more
europepmc +5 more sources
MLC901 in hypoxic-ischemic brain injury patients: A double-blind, randomized placebo-controlled pilot study [PDF]
Medicine (United States), 2023 Background: Hypoxic-ischemic brain injury (HIBI) is a disabling consequence of cardiopulmonary resuscitation, which has no direct treatment except supportive care. Many studies have used pharmacological agents to reduce or stop this disability.
Ali Amini Harandi
exaly +4 more sources
Role of MLC901 in increasing neurogenesis in rats with traumatic brain injury [PDF]
Annals of Medicine and Surgery, 2020 Traumatic brain injury is a dangerous life threatening condition. This study examines the role of MLC901 in increasing neurogenesis. The aim of this study was to demonstrate the role of MLC901 in increasing neuron cell (neurogenesis) in rat with traumatic brain injury using the synaptophysin marker.The synaptophysin levels were measured as a marker for
Rohadi Muhammad Rosyidi +2 more
exaly +4 more sources
The Traditional Chinese Medicine MLC901 inhibits inflammation processes after focal cerebral ischemia [PDF]
Scientific Reports, 2018 AbstractInflammation is considered as a major contributor to brain injury following cerebral ischemia. The therapeutic potential of both MLC601/MLC901, which are herbal extract preparations derived from Chinese Medicine, has been reported both in advanced stroke clinical trials and also in animal and cellular models.
Widmann C +4 more
exaly +5 more sources
Acute and long-term cardioprotective effects of the Traditional Chinese Medicine MLC901 against myocardial ischemia-reperfusion injury in mice [PDF]
Scientific Reports, 2017 AbstractMLC901, a traditional Chinese medicine containing a cocktail of active molecules, both reduces cerebral infarction and improves recovery in patients with ischemic stroke. The aim of this study was to evaluate the acute and long-term benefits of MLC901 in ischemic and reperfused mouse hearts.
Anne Vincent +2 more
exaly +6 more sources
NeuroAid II (MLC901) and polypharmacy in stroke and the risk of hepatotoxicity: a case report [PDF]
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2021 Background NeuroAid II (MLC901) is a promising therapy for stroke patients who present outside of therapeutic window for reperfusion therapy. Studies have proven its efficacy in ischemic stroke; however, data of drug safety and combination with other ...
Anna Misya’il Abdul Rashid +10 more
doaj +2 more sources
Phase II randomised, double-blind, placebo-controlled trial to assess the efficacy and safety of MLC1501 in patients with stroke: the MLC1501 study Assessing Efficacy in post-STrOke Subjects with mOtor deficits (MAESTOSO) study protocol [PDF]
Stroke and Vascular NeurologyBackground MLC1501, consisting of four herbs, that is, Radix Astragali, Radix Angelicae sinensis, Rhizoma Chuanxiong, Radix Polygalae, has the same pharmacological properties as its precursors MLC601 and MLC901 which contain extracts of nine herbs and ...
Narayanaswamy Venketasubramanian +12 more
doaj +2 more sources
Beyond stroke therapy, neuroaid (a chinese herbal) has an effect on cognition and neurogenesis, a bibliometric study [version 2; peer review: 2 approved] [PDF]
F1000ResearchIntroduction NeuroAiD, also known as MLC601 or MLC901, is a Chinese herbal combination used worldwide for stroke treatment. It contains herbal components and five hewan components.
Dwi Arwandi Yogi Saputra +3 more
doaj +2 more sources
Translational Medicine in Acute Ischemic Stroke and Traumatic Brain Injury—NeuroAiD Trials, from Traditional Beliefs to Evidence-Based Therapy [PDF]
BiomoleculesAcute ischemic stroke (AIS) and traumatic brain injury (TBI) are two severe neurological events, both being major causes of death and prolonged impairment.
Narayanaswamy Venketasubramanian +2 more
doaj +2 more sources