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Spatial and Temporal Variability of Mixed Layer Depth (MLD) in Eastern Indian Ocean (EIO): 1998-2020 [PDF]

Jurnal Ilmiah Perikanan dan Kelautan, 2023
Mixed Layer Depth (MLD) plays an important role in various aspects of oceanography. MLD has a characteristic parameter value that is uniform with depth. MLD has an important role for local, regional, and global phenomena.
Amir Yarkhasy Yuliardi, Randi Firdaus
doaj   +3 more sources

John William Trevan’s concept of Median Lethal Dose (LD50/LC50) – more misused than used

Journal of Pre-Clinical and Clinical Research, 2021
Introduction Median lethal dose (MLD) has been a controversial subject among biologists and animal ethicists since its inception in 1927 by Trevan. Toxicologists use MLD (LD50) as the first step to assess the toxicity of a substance.
Sadasivan Kalathil Pillai, Katsumi Kobayashi, Mathews Michael, Thomson Mathai, Bhavana Sivakumar, Parvathy Sadasivan   +5 more
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Observed Anomaly of Temperature and Mixed Layer Depth Associated with the Madden Julian Oscillation (MJO) Active Phase in the Banda Sea, Indonesia

Ilmu Kelautan, 2023
The eastward propagation of atmospheric waves along the equatorial band from the central equatorial Indian Ocean to the western Pacific Ocean passing through the Indonesian Maritime Continent (IMC), known as the intraseasonal Madden Julian Oscillation ...
Nabil Nabil, Agus Saleh Atmadipoera, Dwiyoga Nugroho, Yuli Naulita, Ariane Koch-Larrouy   +4 more
doaj   +1 more source

The importance of early diagnosis and views on newborn screening in metachromatic leukodystrophy: results of a Caregiver Survey in the UK and Republic of Ireland

Orphanet Journal of Rare Diseases, 2022
Metachromatic Leukodystrophy (MLD) is a rare, autosomal recessive lysosomal storage disorder caused by a deficiency of the enzyme arylsulfatase A (ARSA).
Georgina Morton, Sophie Thomas, Pat Roberts, Vivienne Clark, Jackie Imrie, Alexandra Morrison   +5 more
doaj   +1 more source

Understanding caregiver descriptions of initial signs and symptoms to improve diagnosis of metachromatic leukodystrophy

Orphanet Journal of Rare Diseases, 2022
Background Metachromatic leukodystrophy (MLD), a relentlessly progressive and ultimately fatal condition, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency of the enzyme arylsulfatase A (ARSA).
F. Eichler, Caroline Sevin, M. Barth, F. Pang, K. Howie, M. Walz, A. Wilds, C. Calcagni, C. Chanson, L. Campbell   +9 more
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Predicting disease severity in metachromatic leukodystrophy using protein activity and a patient phenotype matrix

Genome Biology, 2023
Background Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused by mutations in the arylsulfatase A gene (ARSA) and categorized into three subtypes according to age of onset. The functional effect of most ARSA mutants remains unknown;
Marena Trinidad, Xinying Hong, Steven Froelich, Jessica Daiker, James Sacco, Hong Phuc Nguyen, Madelynn Campagna, Dean Suhr, Teryn Suhr, Jonathan H. LeBowitz, Michael H. Gelb, Wyatt T. Clark   +11 more
doaj   +1 more source

Total Civilian Deaths During 2003-2015 and Post-Conflict Period in Iraq: Challenges and Achievements of the Medico-Legal Directorate (MLD) in Baghdad

Arab Journal of Forensic Sciences & Forensic Medicine, 2018
Iraq has been involved in several conflicts during the last five decades. The period between 2003-2015 witnessed a dangerous and highly unstable security situation in Iraq resulting in a huge number of civilian fatalities.
Zaid A. Abbas, Ammirah J. Omar, Salah M. Salih, Mustafa Munjid   +3 more
doaj   +1 more source

Evaluating meaningful changes in physical functioning and cognitive declines in metachromatic leukodystrophy: a caregiver interview study

Journal of Patient-Reported Outcomes, 2023
Background Metachromatic leukodystrophy (MLD) is a rare lysosomal storage disease caused by deficient activity of arylsulfatase A (ASA). Treatment options for patients are limited; gene therapy based on haematopoietic stem cell transplantation is the ...
Susan Martin, Nimanee Harris, Dorothy Romanus   +2 more
doaj   +1 more source

Intra-Subject Variability in Mathematical Learning Difficulties

Journal of Cognition, 2022
Objective: Mathematical learning difficulties (MLD) are characterized by difficulties in the understanding and processing of numbers and quantities. While MLD is related mainly to numerical deficits, studies show that this population has several other ...
Sharon Levy, Liat Goldfarb
doaj   +1 more source

Observational Study on the Variability of Mixed Layer Depth in the Bering Sea and the Chukchi Sea in the Summer of 2019

Frontiers in Marine Science, 2022
Based on the CTD data from 58 stations in the Bering Sea and the Chukchi Sea in the summer of 2019, the values of mixed layer depth (MLD) were obtained by using the density difference threshold method.
Xiaohui Jiao, Jicai Zhang, Qun Li, Chunyan Li   +3 more
doaj   +1 more source