Results 71 to 80 of about 24,602 (271)

Clinical trial barriers in neurostimulation for pediatric drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective The NeuroPace responsive neurostimulation (RNS) System effectively treats focal drug‐resistant epilepsy (DRE) in adults but lacks pediatric regulatory approval. Despite effective off‐label pediatric use, systemic device‐trial challenges have impeded label expansion.
Mira C. Hasner, Faith C. Robertson, Nathaniel D. Sisterson, Gabriel Lazaro‐Munoz, Florence T. Bourgeois, James W. Wheless, Steven M. Wolf, Peter C. Warnke, Saadi Ghatan, Joffre Olaya, Catherine J. Chu, Brian N. Lundstrom, Sanjeev V. Kothare, Marytery Fajardo, Marike L. D. Broekman, R. Mark Richardson   +15 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Hubungan variabilitas mixed layer depth kriteria ∆T=0,5 oC dengan sebaran tuna di Samudera Hindia bagian timur

Depik Jurnal, 2013
Samudera Hindia merupakan salah satu perairan yang memiliki peranan penting dalam variabilitas ekosistem perairan termasuk didalamnya sumberdaya perikanan.
Dessy Teliandi, Otong Suhara Djunaedi, Noir Primadona Purba, Widodo Setiyo Pranowo   +3 more
doaj  

Availability of Stage Information From Cancer Registries Providing Data to the European Cancer Information System for Six Selected Cancers

International Journal of Cancer, EarlyView.
The lack of a standardized cancer staging framework across European cancer registries has fragmented epidemiological data, making cross‐border comparisons of cancer indicators difficult. The present study assessed stage reporting for six cancer types from 86 population‐based cancer registries contributing to the European Cancer Information System ...
Cristina Bosetti, Otto Visser, Liesbet Van Eycken, David Pettersson, Joanna Julia Bartnicka, Tadeusz Dyba, Giorgia Randi, Manuela Flego, Raquel N. Carvalho, Manola Bettio, ECIS Working Group, M. Hackl, L. Van Eycken, Z. Valerianova, M. Sekerija, I. Gregoriou, L. Dušek, M. Mägi, A. Brandhorst, J. Müller‐Nordhorn, R. Kirschner‐Schwabe, A. Nennecke, A. Schützendübel, C. Justenhoven, A. Katalinic, D. Murray, D. Camerlengo, R. Galasso, V. Ciullo, G. Sampietro, C. Gasparotti, M. Marola, M. Ferrante, F. Falcini, L. Dal Maso, M. Gambino, P. Michelozzi, L. Boni, M. Villa, V. Napolioni, A. G. Russo, A. C. Fanetti, L. Cavalieri d'Oro, R. Ortolani, G. D'Orsi, M. Fusco, P. Pinna, F. Vitale, F. Manzoni, E. Migliore, L. Bisceglia, G. Cascone, L. Di Furia, R. Cavallo, D. Piras, R. Tumino, M. Mian, G. Candela, A. Caldarella, W. Mantovani, F. Stracci, M. Castelli, M. Sbaraglia, E. Liepina, M. Mousavi, G. Smailyte, O. Visser, J. Macedo, D. Coza, V. Zadnik, A. Boone, A. Lopez De Munain Marques, M. Garrido, P. Gutiérrez Meléndez, F. Botella Quijal, R. Marcos‐Gragera, M. J. Sanchez‐Perez, E. Ramalle Gomara, M. D. Chirlaque Lopez, M. Guevara Eslava, J. Galceran, I. Curjuric, S. Erny, A. Perren, B. Uginet, M. D. Ryser, M. Von Moos, M. Maspoli, M. Mousavi, A. Bordoni, I. Konzelmann, G. Defossez, J. Diebold, S. Rohrmann, D. Bennet, D. Wyn Huws, L. May   +96 more
wiley   +1 more source

Urinary and Faecal Amino‐Acids as Biomarkers for Colorectal Neoplasia in Lynch Syndrome—A Prospective Longitudinal Study

International Journal of Cancer, EarlyView.
ABSTRACT In Lynch syndrome, colonoscopy surveillance for colorectal cancer (CRC) is burdensome and post‐colonoscopy CRCs still occur. Unlike the faecal immunochemical test (FIT), gut metabolomic alterations including amino‐acids have shown potential as non‐invasive biomarkers for detecting both advanced and non‐advanced sporadic colorectal neoplasia ...
Roza C. M. Opperman, Elsa L. S. A. van Liere, Animesh Acharjee, Sudip Mondal, Eduard A. Struys, Andreas Antoniadis, Jasmijn E. B. de Boer, Shivra R. Siriram, Abdellatif Bakkali, Sofie Bosch, Maarten A. J. M. Jacobs, Jan Jacob Koornstra, Johan P. Kuijvenhoven, Monique E. van Leerdam, Manon C. W. Spaander, Tim G. J. de Meij, Evelien Dekker, Dewkoemar Ramsoekh, Nanne K. H. de Boer   +18 more
wiley   +1 more source

Masking level differences under two different measurement conditions: A normative study of young adults

Brain and Behavior
Objective The objective of this study was to determine the gender‐specific normative values of masking level difference (MLD) in healthy young adults for two different measurement conditions. Methods One hundred young adults between the ages of 19 and 25
Sule Cekic, Banu Mujdeci, Kursad Karakoc, Banu Bas   +3 more
doaj   +1 more source

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

Interaural Time and Intensity Difference and the MLD [PDF]

The Journal of the Acoustical Society of America, 1965
Masking-level differences (MLD) for a 600-cps low-pass transient were explored as a function of (1) interaural time difference (Δt; (2) interaural intensity difference (ΔI); and (3) combinations of Δt and ΔI. Masking-level difference here is the difference between two levels of coherent noise (N0), one required to mask a given condition of click, the ...
openaire   +2 more sources

Use of natural ensiling additives with tropical grasses: Physicochemical properties, in vitro fermentation characteristics, and microbial community diversity indices

JSFA reports, EarlyView.
Abstract Background Improving feed quality, availability, and cost‐effectiveness is a big challenge for livestock to ensure animal‐derived food for nutritional security. The aim of the study was to find out how some natural ensiling additives affect physicochemical properties, proximate composition, microbial population, in vitro fermentation ...
A. B. M. Rubayet Bostami, A. S. M. Selim, M. Al‐Mamun, K. M. Islam, M. D. Hossain   +4 more
wiley   +1 more source

Hemodynamic Significance of APEXCT Coronary Angiography Combined With Dynamic CT Myocardial Perfusion Imaging in Assessing Restenosis After Coronary Stenting

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to evaluate the hemodynamic significance of in‐stent restenosis (ISR) by using a combined anatomical‐functional approach with photon‐counting CT coronary angiography (APEX‐CT CTA) and dynamic CT myocardial perfusion imaging (CT‐MPI). We prospectively enrolled 239 symptomatic patients at least 9 months after PCI.
Liang‐Shi Wang, Tian Bai, Ji‐Zhou Yan, Peng‐Yu Guan, Li‐Juan Wen, Hong Guo, Tian‐Yu Zhang   +6 more
wiley   +1 more source