Results 51 to 60 of about 130,311 (282)

Accumulation of Major Life Events in Childhood and Adult Life and Risk of Type 2 Diabetes Mellitus. [PDF]

PLoS ONE, 2015
The aim of the study was to estimate the effect of the accumulation of major life events (MLE) in childhood and adulthood, in both the private and working domains, on risk of type 2 diabetes mellitus (T2DM).
Jolene Masters Pedersen, Naja Hulvej Rod, Ingelise Andersen, Theis Lange, Gry Poulsen, Eva Prescott, Rikke Lund   +6 more
doaj   +1 more source

Open problem: Tightness of maximum likelihood semidefinite relaxations [PDF]

, 2014
We have observed an interesting, yet unexplained, phenomenon: Semidefinite programming (SDP) based relaxations of maximum likelihood estimators (MLE) tend to be tight in recovery problems with noisy data, even when MLE cannot exactly recover the ground ...
Bandeira, Afonso S., Khoo, Yuehaw, Singer, Amit   +2 more
core  

Digital Surface‐Enhanced Raman Scattering With Event Counting and Spectrum Learning for Label‐Free Protein Quantification

Advanced Intelligent Systems, EarlyView.
A statistical and machine learning‐assisted surface‐enhanced Raman scattering (SERS) framework is developed for label‐free quantification of low‐abundance analytes, including proteins. Combining digital SERS event counting with binomial regression and an artificial neural network (ANN) trained on full spectra, the approach achieves picomolar detection ...
Eni Kume, James Rice
wiley   +1 more source

Asymptotics of the discrete log-concave maximum likelihood estimator and related applications

, 2012
The assumption of log-concavity is a flexible and appealing nonparametric shape constraint in distribution modelling. In this work, we study the log-concave maximum likelihood estimator (MLE) of a probability mass function (pmf).
Balabdaoui, Fadoua, Jankowski, Hanna, Pavlides, Marios, Rufibach, Kaspar   +3 more
core   +1 more source

Autoantibodies to Joint‐Related Peptides Are Associated with Onset of Rheumatoid Arthritis in Presymptomatic Seronegative Individuals

Arthritis &Rheumatology, Accepted Article.
Objective To identify autoantibodies in presymptomatic individuals that associate with the onset of rheumatoid arthritis (RA), and to distinguish early RA from osteoarthritis (OA), particularly in individuals lacking classic RA serological markers. Methods We analyzed serum and plasma from three cohorts: pre‐symptomatic individuals who later developed ...
Outi Sareila, Linda Johansson, Anders Lundquist, Monica Leu Agelii, Lei Cheng, Yibo He, Erik Lönnblom, Maria Andersson, Jan Kihlberg, Anders Esberg, Inger Gjertsson, Rikard Holmdahl, Solbritt Rantapää‐Dahlqvist   +12 more
wiley   +1 more source

Simulation Study of Bayesian Zero Inflated Poisson Regression

Cauchy: Jurnal Matematika Murni dan Aplikasi
Bayesian merupakan salah satu metode estimasi parameter yang dapat diaplikasikan pada ukuran sampel yang kecil. Zero Inflated Poisson merupakan salah satu metode untuk menganalisis data Poisson yang mengalami overdispersion.
Candra Rezzing Weni Utomo, Achmad Efendi, Ni Wayan S. Wardhani   +2 more
doaj   +1 more source

Restricted Tweedie stochastic block models

Canadian Journal of Statistics, EarlyView.
Abstract The stochastic block model (SBM) is a widely used framework for community detection in networks, where the network structure is typically represented by an adjacency matrix. However, conventional SBMs are not directly applicable to an adjacency matrix that consists of nonnegative zero‐inflated continuous edge weights.
Jie Jian, Mu Zhu, Peijun Sang
wiley   +1 more source

Multilayered epithelium in a rat model and human Barrett's esophagus: Similar expression patterns of transcription factors and differentiation markers

BMC Gastroenterology, 2008
Background In rats, esophagogastroduodenal anastomosis (EGDA) without concomitant chemical carcinogen treatment leads to gastroesophageal reflux disease, multilayered epithelium (MLE, a presumed precursor in intestinal metaplasia), columnar-lined ...
Yang Chung S, Su Yinghao, Ma Yan, Liu Ba, Qin Rong, Chen Xiaoxin, Glickman Jonathan N, Odze Robert D, Shaheen Nicholas J   +8 more
doaj   +1 more source

The anti-obesity effect of mulberry leaf (Mori Folium) extracts was increased by bioconversion with Pectinex

Scientific Reports, 2022
Mulberry leaf (Mori Folium) extract (MLE) is known to have anti-obesity effects. In this study, the enhanced effects of MLE after bioconversion treatment using Pectinex (BMLE) on obesity were explored, and the underlying mechanisms were investigated ...
Joo-Hui Han, Hyung-Won Lee, Sang-Hyuk Jung, Chong Woon Cho, Tae Jeong Kim, Jong Seong Kang, Chang-Seon Myung   +6 more
doaj   +1 more source

Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP

Canadian Journal of Statistics, EarlyView.
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang, Steven Chen, Raymond Balise, Jiming Jiang, Nagi Ayad, J. Sunil Rao   +5 more
wiley   +1 more source