Results 21 to 30 of about 3,296,150 (267)

HIV Stigma: Perspectives from Kenyan Child Caregivers and Adolescents Living with HIV

Journal of the International Association of Providers of AIDS Care, 2017
Stigma shapes all aspects of HIV prevention and treatment, yet there are limited data on how HIV-infected youth and their families are affected by stigma in sub-Saharan Africa. The authors conducted a qualitative study using focus group discussions among
Megan Song McHenry MD, Winstone M. Nyandiko MBChB, MMed, MPH, Michael L. Scanlon MPH, Lydia J. Fischer BA, Carole I. McAteer MS, Josephine Aluoch BA, Violet Naanyu PhD, Rachel C. Vreeman MD, MS   +7 more
doaj   +1 more source

Harvesting amino acid doped KDP crystal by temperature and time control using AVR microcontroller

Results in Chemistry, 2020
The significant advances in the fascinating field of solid state physics which is largely concerned with crystal world. The growth of crystal was reported along growth zone plane 〈011〉 and 〈101〉 by seed rotating crystal method under specially made ...
V.R. Raghorte, G.C. Wakde, N.S. Meshram, K.G. Rewatkar   +3 more
doaj   +1 more source

HIV-Related Knowledge, Attitudes, Behaviors and Experiences of Kenyan Adolescents Living with HIV Revealed in WhatsApp Group Chats

Journal of the International Association of Providers of AIDS Care, 2021
Introduction: Mobile technologies represent a scalable platform for delivering knowledge and interventions targeting adolescents living with HIV (ALWH) in low and middle income countries.
Ashley Chory MPH, Winstone Nyandiko MBChB, Mmed, Roxanne Martin MPH, Josephine Aluoch MS, Michael Scanlon MS, MPH, Celestine Ashimosi MBChB, Mmed, Tabitha Njoroge MBChB, Mmed, Carole McAteer MBChB, Mmed, Edith Apondi MBChB, Mmed, Rachel Vreeman MD, MS   +9 more
doaj   +1 more source

Establishment of an Ex Vivo Inflammatory Osteoarthritis Model With Human Osteochondral Explants

Frontiers in Bioengineering and Biotechnology, 2021
Osteoarthritis (OA) is the most common degenerative joint disease without clear pathophysiological mechanism and effective drugs for treatment. Although various animal models exist, the translation of the outcome into clinics remains difficult due to ...
Kaihu Li, Kaihu Li, Penghui Zhang, Penghui Zhang, Yong Zhu, Mauro Alini, Sibylle Grad, Zhen Li   +7 more
doaj   +1 more source

QM/MM Modeling of the Flavin Functionalization in the RutA Monooxygenase

Molecules, 2023
Oxygenase activity of the flavin-dependent enzyme RutA is commonly associated with the formation of flavin-oxygen adducts in the enzyme active site. We report the results of quantum mechanics/molecular mechanics (QM/MM) modeling of possible reaction pathways initiated by various triplet state complexes of the molecular oxygen with the reduced flavin ...
Bella Grigorenko, Tatiana Domratcheva, Alexander Nemukhin   +2 more
openaire   +3 more sources

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Multiscale QM/MM modelling of catalytic systems with ChemShell

Physical Chemistry Chemical Physics, 2023
We present an overview of recent developments in the computational chemistry environment ChemShell for multiscale QM/MM modelling of biomolecular and materials catalysts, together with a survey of recent catalysis applications using ChemShell.
Lu, Y, Sen, K, Yong, C, Gunn, DSD, Purton, JA, Guan, J, Desmoutier, A, Abdul Nasir, J, Zhang, X, Zhu, L, Hou, Q, Jackson-Masters, J, Watts, S, Hanson, R, Thomas, HN, Jayawardena, O, Logsdail, AJ, Woodley, SM, Senn, HM, Sherwood, P, Catlow, CRA, Sokol, AA, Keal, TW   +22 more
openaire   +4 more sources

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen, Kristian Juul Sandahl, Lene Karlsson, Jonas Abrahamsson, Nira Arad‐Cohen, Daniel Cheuk, Barbara De Moerloose, Linda Fogelstrand, Jose Maria Fernandez Navarro, Bianca F. Goemans, Kirsi Jahnukainen, Gertjan Kaspers, Zhanna Kovalova, Monica Cheng Munthe‐Kaas, Ulrika Norén‐Nyström, Josefine Palle, Ramune Pasauliene, Cornelis Jan Pronk, Kadri Saks, Anne Tierens, Henrik Hasle, Kristian Løvvik Juul‐Dam   +21 more
wiley   +1 more source

Insight into pericytes in glioblastoma angiogenesis: In vivo tracking by two‐photon microscopy and proteomic profiling

Animal Models and Experimental Medicine
Background Glioblastoma (GBM) is a highly aggressive brain tumor characterized by aberrant angiogenesis and an immunosuppressive microenvironment. Pericytes are aberrantly recruited but their spatiotemporal roles and molecular changes remain unclear ...
Qinghong Wang, Chengyan Ma, Xinpei Wang, Mengyuan Li, Xingjiu Yang, Ran Gao   +5 more
doaj   +1 more source