Results 211 to 220 of about 6,225,982 (226)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A Topographical Anatomical Description of the Orbit of the Alpaca, Vicugna pacos. [PDF]

Vet Ophthalmol
Weis S, Maierl J.
europepmc   +1 more source

Temporal and clinical heterogeneity of double M-protein multiple myeloma: diagnostic and treatment-emergent phenotypes. [PDF]

Front Oncol
Chen D, Yao F.
europepmc   +1 more source

Through-the-scope twin clip for closure of gastric endoscopic full-thickness resection defects: a retrospective comparative study. [PDF]

Ann Med
Xia W, Chen Y, Wang Q, Zhang X, Lv J, Zhang S.   +5 more
europepmc   +1 more source

Myeloid-derived suppressor cells in multiple myeloma: mechanistic insights and therapeutic implications. [PDF]

Front Immunol
Wen J, Zhou Q, Yue J, Zhang Y, Zheng Y, Xu F.   +5 more
europepmc   +1 more source