Results 161 to 170 of about 11,212,458 (259)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Distal Phalanx Depth Variation and Implications for Zone I Flexor Tendon Anchor Repairs: A CT and X-Ray Comparative Study. [PDF]

Hand (N Y)
Geddada M, Gilpin B, Gao D, McCarron L, Hughes I, Bindra R.   +5 more
europepmc   +1 more source

Microwave, mm, and sub-mm measurement capability [PDF]

Waters, J. W.
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Does graft thickness affect outcomes in massive rotator cuff repairs with on-lay and bridging graft augmentation? A systematic review and meta-analysis. [PDF]

Shoulder Elbow
Sain B, Suryawanshi S, Kothari M, Malhas A, Patel V.   +4 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Implant Survival and Radiographic Outcome of a Novel Implant With a Machined Long Neck: A 1-Year Retrospective Study. [PDF]

Clin Implant Dent Relat Res
Lee SJ, Lee J, Ko YC, Koo KT, Gargallo-Albiol J, Dinu C, An HW, Jung JA, Kim HY, Park K.   +9 more
europepmc   +1 more source

Anterior abdominal wall cysticercosis-the role of high-resolution USG

Indian Journal of Radiology and Imaging, 2008
Amit Mittal, Sanjeev Gupta, Vinod Mehta, Rakesh Gupta   +3 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

<i>Solenopsis sphaciotica</i> (Campanulaceae) a new species from Crete. [PDF]

PhytoKeys
Cambria S, Giusso Del Galdo G, Minissale P, Siracusa G, Brullo S.   +4 more
europepmc   +1 more source