Results 31 to 40 of about 132,712 (265)

Simple one-pot fabrication of ultra-stable core-shell superparamagnetic nanoparticles for potential application in drug delivery [PDF]

open access: yes, 2012
Ultrastable superparamagnetic core-shell nanoparticles of average diameter 80 nm have been fabricated via a simple one-pot method involving superparamagnetic iron oxide nanoparticles (SPIONs) core ([similar]50 nm in diameter) and lipid bilayer shell by ...
Al-Jamal   +43 more
core   +1 more source

Modeling and enhanced control of hybrid full bridge–half bridge MMCs for HVDC grid studies [PDF]

open access: yes, 2020
Modular multilevel converters (MMCs) are expected to play an important role in future high voltage direct current (HVDC) grids. Moreover, advanced MMC topologies may include various submodule (SM) types. In this sense, the modeling of MMCs is paramount
Forner, Jaume, Vidal-Albalate, Ricardo
core   +1 more source

Myths of MTAS and MMC [PDF]

open access: yesJournal of the Royal Society of Medicine, 2007
As we move ever closer to the start of August, there remains no sign that the MTAS (Medical Training Application Service) debacle will end. In the months since this sorry episode began, doctors have been united in a way never seen before,1 and the common goals of those professionals who have invested so much of themselves in the NHS are becoming ...
Jonathan D, Rohrer   +2 more
openaire   +3 more sources

Clinical Spectrum of Pregnancy Related Dermatoses in a Tertiary Care Hospital in Western India

open access: yesNational Journal of Community Medicine, 2020
Introduction: Pregnancy is characterized by altered endocrine, metabolic, and immunologic milieus resulting in multiple cutaneous changes, both physiologic and pathologic.
Pooja Agarwal   +4 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector. [PDF]

open access: yes, 2010
One of the major hurdles for the development of gene therapy for Fanconi anemia (FA) is the increased sensitivity of FA stem cells to free radical-induced DNA damage during ex vivo culture and manipulation.
Adair, J   +10 more
core   +2 more sources

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz   +25 more
wiley   +1 more source

MMC based SST [PDF]

open access: yes2015 IEEE 13th International Conference on Industrial Informatics (INDIN), 2015
This work was supported in part by the Research, Technological Development and Innovation Programs of the Spanish Ministries of Science and Innovation and of Economy and Competitiveness, under grants MICINN- 10-CSD2009- 00046 and ENE2013-48727-C2-1-R, and by the European Commission FP7 Large Project NMP3-LA-2013-604057, under grant UE-14-SPEED ...
Fernando Briz   +5 more
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

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