Results 61 to 70 of about 66,643 (281)

Modification‐Selective Inhibition of Succinate Dehydrogenase a Enables Tumor‐Restricted Mitochondrial Modulation

Advanced Science, EarlyView.
This work identifies acetylation‐dependent SDHA homeostasis as a determinant of tumor‐specific metabolic vulnerability. Guided by this mechanism, a modification‐selective inhibitor, ZPI‐3, selectively targets non‐acetylated SDHA, achieving tumor‐restricted SDH inhibition and effective bladder cancer control. Differential responses in clinical specimens
Kaikai Xu, Lulu Kong, Kebin Ye, Xinlu Bao, Haowen Liu, Ning Wang, Yongming Deng, Wei Wang, Shaohua Wei, Lin Zhou   +9 more
wiley   +1 more source

Outcome trabekulektomi terhadap kontrol tekanan intraokular

Majalah Kedokteran Andalas, 2018
Tujuan: Membandingkan outcome pada tindakan trabekulektomi, trabekulektomi dengan MMC dan trabekulektomi dengan ekstraksi katarak. Metode:  Penelitian retrospektif dari rekam medis pasien poliklinik Mata RSUP Dr. M. Djamil Padang.
Muhammad Syauqie, Fitratul Ilahi
doaj   +1 more source

Observation of Magnetic‐Anisotropy Crossover and High‐Temperature Skyrmions in the Dirac Magnet Fe3Ge with a Distorted Kagome Lattice

Advanced Science, EarlyView.
A temperature‐driven magnetic anisotropy crossover is revealed in the Dirac kagome magnet Fe3Ge with a distorted kagome lattice. The transition from easy‐plane to easy‐axis magnetic anisotropy stabilizes robust Bloch‐type skyrmions over an exceptionally wide temperature window of 375–650 K.
Yalei Huang, Xiaowei Lv, Bin Li, Chunqiang Xu, Dhanarajagopal Alltrin, Xiaoxuan Ma, Wanting Yang, Wei Zhou, Xiangzhuo Xing, Wen‐Chin Lin, Raman Sankar, Michael Smidman, Shixun Cao, Dong Qian, Renchao Che, Xiaofeng Xu   +15 more
wiley   +1 more source

Hierarchical Flux‐Protection Engineering Stabilizes Oxidation‐Prone Metabolic Nodes for High‐Level Curcumin Biosynthesis

Advanced Science, EarlyView.
Flux‐protection engineering stabilizes an oxidation‐prone L‐DOPA node in engineered E. coli by combining acid‐adapted chassis evolution, respiratory‐chain modulation, enzyme‐level flux matching, and pH–DO control. Carbon is redirected from oxidative browning to productive biosynthesis, enabling 1075.2 mg/L curcumin and demonstrating transferability to ...
Jianbin Chen, Qihang Chen, Shurong Zhang, Yajuan Su, Xiaoyi Zou, Ke Wang, Shike Liu, Qian He, Liang Zhang, Weizhu Zeng, Jingwen Zhou   +10 more
wiley   +1 more source

A new approach to open-circuit fault diagnosis of MMC sub-module

Systems Science & Control Engineering, 2020
This paper is concerned with the open-circuit fault diagnosis of MMC sub-module. To estimate the arm current accurately in normal and fault cases, a sliding mode observer is designed based on Lyapunov theory.
Baoye Song, Gaoru Qi, Lin Xu
doaj   +1 more source

Mapping Embryonic Mouse Lung Development Using Enhanced Spatial Transcriptomics

Advanced Science, EarlyView.
The mammalian lung contains ∼50 cell types arranged along the airway epithelium. Here, deterministic barcoding sequencing (DBiT‐seq) is optimized to nearly double transcript recovery, enabling highly sensitive spatial mapping of the embryonic mouse lung.
Pengfei Zhang, Benjamin K. Law, Niles Huang, Katharine Goodwin, Celeste M. Nelson, Michelle M. Chan   +5 more
wiley   +1 more source

Enhanced Hydrogen Evolution Activity of MoS2 Through Solid Solution Modification of Its Edge Sites With Ruthenium

Angewandte Chemie, EarlyView.
Modulating the edge sites of molybdenum disulfide significantly boosts hydrogen production. By depositing Ru to form an edge‐coordinated solid solution, we accelerate water dissociation and shift the hydrogen evolution reaction pathway to Volmer–Tafel.
Jinsong Zhou, Tsz Kei Leung, Denis A. Kuznetsov, Christoph R. Müller, Lei Ran, Yingguang Zhang, Xin Li, Gang Li, Yifan Xu, Keda Chen, Qinglan Tang, Yaoyang Yu, Michael K.H. Leung   +12 more
wiley   +2 more sources

ASSOCIATION OF VERTEBRAL FRACTURES AND HIP FRACTURES IN PATIENTS WITH OSTEOPOROSIS

National Journal of Medical Research, 2014
Background: Osteoporosis is quite common disease among aged in India. Studies indicate that vertebral fractures are probably the most common fragility fractures and that they are often followed by a second fracture.
Deepak D Chitragar, Sadik I Shaikh
doaj  

Cr1/4NbSe2‐Single Crystal Growth and Evolution of Antiferromagnetic Correlated States

Advanced Science, EarlyView.
High‐quality single crystals Cr1/4NbSe2 were synthesized and comprehensively characterized for the first time. Advanced structural, electronic, and magnetic measurements uncover a correlated antiferromagnetic state, resolving longstanding inconsistencies regarding magnetic behavior derived from earlier polycrystal studies.
Nour Abdelrahman, Bastian Rubrecht, Matheus Felipe de Souza Barbosa, Mahdi Behnami, Dmitriy Efremov, Daniel Wolf, Martin Valldor, Alexey A. Popov, Stanislav M. Avdoshenko, Marco Naumann, Martin Knupfer, Vladislav Kataev, Alexey Alfonsov, Anja U. B. Wolter, Michael Mertig, Bernd Büchner, Silke Hampel   +16 more
wiley   +1 more source

SoC-based Real-Time Simulation of MMC Electromagnetic Transient

, 2022
With the rapid emergence and profound penetration of modular multilevel converters (MMC) in power system, the real-time simulation technology of electromagnetic transient (EMT) becomes very important.
Zhao SONG, Guangzeng YOU, Zihang GUI, Lingfang LI, Xinchun ZHU, Dewu SHU   +5 more
core   +1 more source