Matrix Metalloproteinase Inhibition in Melanoma. [PDF]
ABSTRACT Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix (ECM) and are found to participate in all stages of tumour progression including modifying signalling pathways, regulating cytokines and promoting tumour growth, particularly by inducing angiogenesis and facilitating cancer spread.
Zhang E, Thakur V, Bedogni B.
europepmc +2 more sources
Bioresponsive Hyaluronic Acid-Based Hydrogel Inhibits Matrix Metalloproteinase-2 in Glioblastoma Microenvironment. [PDF]
A bioresponsive hydrogel based on hyaluronic acid crosslinked with a MMP inhibitor (HA‐MMPI) is generated to modulate the glioblastoma multiforme (GBM) microenvironment. In preliminary tests with 3D U87 models, HA‐MMPI selectively inhibits MMP‐2, reducing cell migration.
Barbugian F +13 more
europepmc +2 more sources
Can the MMPI Predict Adult ADHD? An Approach Using Machine Learning Methods
(1) Background: Adult attention-deficit/hyperactivity disorder (ADHD) symptoms cause various social difficulties due to attention deficit and impulsivity.
Sunhae Kim, Hye-Kyung Lee, Kounseok Lee
doaj +1 more source
Two Views of Invalid Response Set and Malingering Attributions in Forensic Assessment: Credibility and Non-Credibility. [PDF]
ABSTRACT This article reviews two major sets of six articles on malingering and invalid response set, which have diametrically opposite conclusions on the value of performance and symptom validity tests (PVTs and SVTs) in forensic and related disability assessments (FDRA). First, we review the six‐article series by the Leonhards, which takes the stance
Young G, Erdodi LA, Giromini L.
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Révision et validation des échelles cliniques du TMDP // Revision and validation of the TMDP clinical scales [PDF]
La construction d’échelles avec les questionnaires de personnalité a beaucoup évolué depuis la toute première version du Minnesota Multiphasic Personality Inventory. Avec les questionnaires à réponses dichotomiques vrai-faux, les échelles ont d’abord été
Cloutier, Jacques +3 more
doaj +1 more source
Gaming addiction, definition, and measurement: a large-scale empirical study [PDF]
Aims: Although the general public appears to have embraced the term 'video game addiction', the scientific debate as to whether 'gaming addiction' can actually be considered an addiction similar to substance addictions of DSM-IV is still unsettled. To
Griffiths, MD +3 more
core +1 more source
An MMPI-2 hopelessness scale: Construction, initial validation and implication for suicide risk
This study documents the development of a new MMPI-2 scale, Hopelessness (Hp), designed to identify suicide risk in examinees who, for whatever reason, may be reluctant to endorse items reflecting explicit suicide content.
David S. Nichols +4 more
doaj +1 more source
Innovative Tracheal Tube Design Enhances Oral Health in Intubated Patients. [PDF]
ABSTRACT Endotracheal intubation is a crucial intervention for mechanically ventilated patients in the intensive care unit (ICU). However, the presence of the tube and bite block in the mouth significantly raises the risk of mucosal pressure injuries (MMPI) and other oral complications.
Wang L +5 more
europepmc +2 more sources
The relationship between attentional processing of emotional information and personality : a comparison between older and younger adults [PDF]
Older adults have been found to focus more on positive and less on negative information compared to younger adults. Yet, results on this attentional positivity effect are inconsistent.
De Raedt, Rudi +3 more
core +2 more sources
Severe depression when everything else is dismissed. A case
Introduction Simulation is a deliberate counterfeiting of physical or psychological symptoms in order to obtain a secondary gain or external incentive, like evading from military service, scape from work, obtain economic compensations or avoid criminal
L. Soldado Rodriguez +2 more
doaj +1 more source

