Results 221 to 230 of about 88,142 (297)

Treatment‐free remission in CML patients with prior TKI failure is not influenced by previous BCR::ABL1 kinase domain mutations

British Journal of Haematology, EarlyView.
Simone Claudiani, Silvia Metelli, Myrto Katraki, Fiona Fernando, Andrew J. Innes, Chloe Hayden, Dragana Milojkovic   +6 more
wiley   +1 more source

GNOCHI: Generative Neural mOdel for Close Human‐Human Interactions

Computer Graphics Forum, EarlyView.
Abstract Creating realistic 3D human‐human interactions in virtual environments is challenging due to the high degrees of freedom in human body and the need for physically accurate poses that do not collide with each other. Traditional methods for humanhuman interaction are based on motion tracking or 3D body reconstruction, but lack generative ...
Gonzalo Gómez‐Nogales, Marc Comino‐Trinidad, Andrés Casado‐Elvira, Dan Casas   +3 more
wiley   +1 more source

Two distinct Okazaki fragment failure modes dominate mutagenesis in the absence of flap endonuclease 1. [PDF]

Nat Commun
Lujan SA, Arana ME, Wilkins H, Williams JS, Garbacz MA, Bebenek K, Kunkel TA.   +6 more
europepmc   +1 more source

Subspecies taxonomy reflects social and geographic patterns of taxonomic effort in tetrapods

Conservation Biology, EarlyView.
Abstract Subspecies have been used in conservation biology to account for intraspecific patterns in genetic diversity, which is crucial to long‐term population viability. Although over 3200 subspecies are currently assessed by the International Union for Conservation of Nature Red List, their biological relevance remains controversial.
Jhonny J. M. Guedes, José Alexandre F. Diniz‐Filho, André V. L. Freitas, Mario R. Moura   +3 more
wiley   +1 more source

Machine Learning Analysis of Maternal Mortality Determinants in Nigeria: An Exploratory Study. [PDF]

Int J Health Plann Manage
Olaniran A, Ojo OA, Olubodun T, Al-Mujtaba M, Babalola L, Olaniran GO, Kothapalli A, Nwamata OC, Banke-Thomas A.   +8 more
europepmc   +1 more source

Cystic Fibrosis and Colorectal Cancer Risk: Reprogramming of the Intestinal Epithelial Niche and Cell‐State Plasticity in the CFTR Modulator Era

Cell Proliferation, EarlyView.
In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar, Ines Pankonien, Margarida Amaral, Chee Y. Ooi, Thierry Jardé, Shafagh A. Waters   +5 more
wiley   +1 more source

Patterns of Response to Immune Checkpoint Inhibitors in Sarcomas With High Tumor Burden and/or Mismatch Repair Deficiency. [PDF]

JCO Precis Oncol
Alcindor T, Papke DJ, Venkataraman V, Wagner MJ, Merriam P, Haddox CL, Wagner AJ, Solimini NL, Jambhekar A, George S.   +9 more
europepmc   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Neoadjuvant Chemotherapy Followed by Interval Debulking for Advanced-Stage Endometrial Cancer: Survival Outcome Based on Surgical and Molecular Characteristics. [PDF]

Curr Oncol
Kheil M, Mekkaoui T, Andresan E, Fung G, Miller M, Joseph JG, Wang A, Al Asadi A, Elshaikh M, Ahmad S, Awada A.   +10 more
europepmc   +1 more source