High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast. [PDF]
, 2017 In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule.
Dominska, Margaret +3 more
core +3 more sources
Congenital Rubella Syndrome with Blueberry Muffin Lesions and Extensive Metaphysitis [PDF]
Journal of Clinical and Diagnostic Research, 2014 We report a case of Congenital Rubella Syndrome (CRS) in a newborn. The baby had blueberry muffin skin lesions, long bone metaphysitis and congenital heart defects.
Mohemmed Ajij +2 more
doaj +1 more source
On multiplicity of mappings between surfaces [PDF]
, 2008 Let M and N be two closed (not necessarily orientable) surfaces, and f a continuous map from M to N. By definition, the minimal multiplicity MMR[f] of the map f denotes the minimal integer k having the following property: f can be deformed into a map g ...
Bogatyi, Semeon +2 more
core +3 more sources
Archives of Disease in Childhood, 2000 Live measles and mumps vaccine viruses are cultured in chick embryo fibroblasts and may contain minute amounts of egg related antigens.1-3 In view of this, there has been a longstanding debate on the safety of these vaccines in children with severe allergic reactions to egg. Initially it was believed that such children could safely receive the vaccine;
R, Lakshman, A, Finn
openaire +2 more sources
Characteristics of 5-year-olds who catch-up with MMR: findings from the UK Millennium Cohort Study [PDF]
, 2013 Objectives To examine predictors of partial and full measles, mumps and rubella (MMR) vaccination catch-up between 3 and 5 years. Design Secondary data analysis of the nationally representative Millennium Cohort Study (MCS).
Bedford, Helen +3 more
core +2 more sources
Vaccines, 2019 To assess correlates of protection against measles and against subclinical measles virus (MV) infection, we recruited once-vaccinated children from geographic regions associated with increased MV circulation and/or at schools with low vaccination ...
Tom Woudenberg +9 more
doaj +1 more source
A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803. [PDF]
, 2017 PurposeTumor levels of thymidylate synthase (TS), a target of 5-fluorouracil (5-FU)-based chemotherapy for colorectal cancer, have been studied as a predictive or prognostic biomarker with mixed results.Patients and methodsTumor TS levels were ...
Bertagnolli, Monica M +13 more
core +1 more source
Measles vaccination in an increasingly immunized and developed world
Human Vaccines & Immunotherapeutics, 2019 Increased measles immunization has led to a significant decline in measles incidence and mortality. During 2016 it is estimated that fewer than 100,000 died from measles for the first time in recorded history.
David T. S. Hayman
doaj +1 more source
Parametric analysis and its effect on machinability for Incoloy 800 with copper electrode [PDF]
ITM Web of ConferencesIn Electric Spark Machining, choice of manufacturing constraints is a necessary feature. This Electrical Spark Machining is an advanced process in all manufacturing processes. For the manufacturing of sophisticated parts, which require accurate machining
Patel Dhaval A. +2 more
doaj +1 more source
Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair and p53. [PDF]
, 2013 The antitumor prodrug Temozolomide is compromised by its dependence for activity on DNA mismatch repair (MMR) and the repair of the chemosensitive DNA lesion, O6-methylguanine (O6-MeG), by O6-methylguanine-DNA-methyltransferase (EC 2.1.1.63, MGMT). Tumor
Arris C. E. +42 more
core +1 more source