Results 161 to 170 of about 55,884 (291)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Bilateral persistence of the proatlantal intersegmental arteries in moyamoya syndrome: illustrative case. [PDF]

J Neurosurg Case Lessons
Higginbotham A, Napoletano D, Reed A, De Stefano F, Fry L, Williams A, Ebersole K, Peterson J.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Hsp70 is phosphorylated in a conserved response to DNA damage and contributes to cell cycle control. [PDF]

Elife
Moss T, Wooldredge A, Bhakta K, Cronin M, Gestwicki JE, Mukherjee S.   +5 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Erste Erfahrungen mit einem Low Cost MMS

, 2011
In diesem Bericht wird ein Low Cost Mobile Mapping System (MMS) vorgestellt, das aus einem SICK-Laserscanner vom Typ LMS511-20100PRO, einem GPS-Empfänger und einem Xsens Sensor vom Typ MTi-G besteht.
Yao, L.; Ohlmann-Lauber, J.; Reith, C.
core  

Clinical Evaluation <i>Versus</i> Clinical Evaluation With Dermoscopy in Malignant Skin Neoplasms Diagnosis. [PDF]

In Vivo
Majewska O, Kulig P, Brzewski P, Kulig J, Markiewicz A.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

MMS Games and Player Perceptions

, 2018
The purpose of this research is to study the impact of playing modern military shooter (MMS) video games, and how they influence the perceptions of players. This is specifically in terms of how patriotic they consider themselves to be and what they think
Bourassa, Kyle, Pettyjohn, David
core  

The Upgrading Clinical Subtype Classification of Basal Cell Carcinoma is Useful to Correlate With Its Histologic Subtype and Local Invasiveness. [PDF]

Ann Dermatol
Lee J, Cha S, Ko HC, Kim BS, Kim MB, Kim HS.   +5 more
europepmc   +1 more source