Results 241 to 250 of about 152,985 (282)

Estimating the Opportunity for Early Detection of Ovarian Cancer Using Individual-Patient Data from a Large Randomized Controlled Trial. [PDF]

Cancer Epidemiol Biomarkers Prev
Ryser MD, Holloway ST, Morsomme R, Ryan A, Apostolidou S, Gentry-Maharaj A, Gogebakan KC, Lange J, Xu J, Menon U, Etzioni R.   +10 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

The chromatin regulator HELLS mediates SSB repair and responses to DNA alkylation damage. [PDF]

Nucleic Acids Res
Joseph JT, Wright CM, Peixoto E, Shibata E, Khan A, Li Y, Neidigk JSR, Chen BR, Tufail S, Mujawar AA, Decker O, Kadali KR, Imtiaz A, Jones BA, Zhang Y, Gradilone SA, Lewis ZA, Contreras-Galindo R, Sen A, Dutta A, Czaja W.   +20 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Hyperspectral Imaging for Lateral Tumour Demarcation of High-risk Basal Cell Carcinomas during Mohs Micrographic Surgery. [PDF]

Acta Derm Venereol
Ceder H, Salmivuori M, Pölönen I, Paoli J, Neittaanmäki N.   +4 more
europepmc   +1 more source

2-Phase MMS experiments - 2nd degree regularisation

, 2018
Quentin Parsons
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Direct observations of cross-scale energy transfer driven by multiple-ion interactions in space plasmas. [PDF]

Nat Commun
Liu ZY, Zong QG, Wang S, Zhou XZ, Yue C.
europepmc   +1 more source

Existence of MMS Allocations of Mixed Manna [PDF]

Kevin Hsu
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source